Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29430364 | 1.00 | CA12 (0.43) | CA12CA1CA9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL15380918 | 0.99 | CA12 (0.43) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL24621959 | 0.93 | CA12 (0.44) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL11350787 | 0.88 | KDM4E (0.46) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL31301807 | 0.88 | KDM4E (0.46) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL29544027 | 0.88 | CA1 (0.50) | CA12CA1CA9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11350984 | 0.88 | CA1 (0.46) | CA12CA1CA9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29692762 | 0.87 | CA1 (0.49) | CA12CA1CA9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11482111 | 0.87 | CA12 (0.45) | CA12CA1CA9KDM4EALDH1A1 | |
| SCHEMBL29543787 | 0.86 | CA1 (0.53) | CA12CA1CA9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
| US-7319086-B1 | Method of prophylaxis and treatment and agents useful for same | UNIVERSITY OF SYDNEY (AU) | 2008-01-15 | — | — | US | disclosed |
| EP-1088081-B1 | PRODUCTION OF UROKINASE IN PLANT-BASED EXPRESSION SYSTEMS | CROPTECH DEV CORP (US) | 2005-03-09 | — | — | EP | disclosed |
| EP-1189630-A4 | A METHOD OF PROPHYLAXIS AND TREATMENT AND AGENTS USEFUL FOR SAME | UNIV SYDNEY (AU) | 2004-08-18 | — | — | EP | disclosed |
| US-20040111765-A1 | Production of urokinase in plant-based expression systems | OISHI KAREN K (US) | 2004-06-10 | — | — | US | disclosed |
| EP-1189630-A1 | A METHOD OF PROPHYLAXIS AND TREATMENT AND AGENTS USEFUL FOR SAME | University of Sydney (AU) | 2002-03-27 | — | — | EP | disclosed |
| EP-1088081-A1 | PRODUCTION OF UROKINASE IN PLANT-BASED EXPRESSION SYSTEMS | Croptech Development Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-2000072875-A1 | A METHOD OF PROPHYLAXIS AND TREATMENT AND AGENTS USEFUL FOR SAME | UNIVERSITY OF SYDNEY (AU) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000000624-A9 | PRODUCTION OF UROKINASE IN PLANT-BASED EXPRESSION SYSTEMS | CROPTECH DEV CORP (US) | 2000-11-02 | — | — | WO | disclosed |
| WO-2000000624-A1 | PRODUCTION OF UROKINASE IN PLANT-BASED EXPRESSION SYSTEMS | CROPTECH DEVELOPMENT CORPORATION (US) | 2000-01-06 | — | — | WO | disclosed |
| WO-1994012204-A1 | ANTICOAGULANT PROTEINS | MERCK & CO., INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| EP-0000063-B1 | DIPEPTIDE DERIVATIVES OF 7-(N-ALPHA-SUBSTITUTED OR NON-SUBSTITUTED X-ARGINYL)-AMINO-4-METHYL-COUMARIN | AJINOMOTO CO., INC. (JP) | 1981-06-10 | — | — | EP | disclosed |
| EP-0000063-A1 | Dipeptide derivatives of 7-(N-alpha-substituted or non-substituted X-arginyl)-amino-4-methyl-coumarin | AJINOMOTO CO., INC. (JP) | 1978-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | CA12 4856/4885CA1 4868/4885CA9 4872/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | CA12 1810/4885CA1 3434/4885CA9 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.