SCHEMBL3363334

SCHEMBL3363334

COC(=O)c1c(O)c(O)c(C(=O)O)n1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 6/20 0.53
AR P10275 1/20 0.50
ALDH1A1 P00352 3/20 0.49
MAPT P10636 2/20 0.49
GAA P10253 2/20 0.49
PKM P14618 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
THRB P10828 1/20 0.47
TSHR P16473 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP1A2 P05177 1/20 0.44
NOTUM Q6P988 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182807 0.95 MAPK8 (0.57) MAPK8ARALDH1A1MAPTGAA
SCHEMBL182646 0.87 FOLH1 (0.49) ALDH1A1MAPTGAAPKMTSHR
SCHEMBL182493 0.81 MAPT (0.62) ALDH1A1MAPTGAAPKMTDP1
SCHEMBL23760001 0.81 MAPK8 (0.56) MAPK8ALDH1A1MAPTGAAPKM
SCHEMBL34462088 0.81 MAPK8 (0.52) MAPK8ARALDH1A1MAPTGAA
SCHEMBL2934311 0.79 MAPK8 (0.48) MAPK8ARALDH1A1MAPTGAA
SCHEMBL2723479 0.77 MAPK8 (0.51) MAPK8ARALDH1A1MAPTGAA
SCHEMBL15458866 0.76 DRD2 (0.48) MAPK8ARALDH1A1MAPTGAA
SCHEMBL4710289 0.74 MAPK8 (0.63) MAPK8
SCHEMBL4236086 0.73 MAPK8 (0.43) MAPK8ARALDH1A1MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080055701-A1 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2008-03-06 US claimed
US-20100124702-A1 High Energy Composite Cathodes for Lithium Ion Batteries PHYSICAL SCIENCES, INC. (US) 2010-05-20 US disclosed
US-7547658-B2 Switchable window based on electrochromic polymers UNIVERSITY OF WASHINGTON (US) 2009-06-16 US disclosed
US-7505191-B2 Electrochromic monomers and polymers for a switchable window UNIVERSITY OF WASHINGTON (US) 2009-03-17 US disclosed
US-20080055701-A1 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2008-03-06 US disclosed
US-20070268550-A1 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2007-11-22 US disclosed
US-7256923-B2 Switchable window based on electrochromic polymers UNIVERSITY OF WASHINGTON (US) 2007-08-14 US disclosed
EP-1756658-A2 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS University of Washington (US) 2007-02-28 EP disclosed
US-20050200935-A1 Switchable window based on electrochromic polymers UNIVERSITY OF WASHINGTON (US) 2005-09-15 US disclosed
WO-2005084350-A2 SWITCHABLE WINDOW BASED ON ELECTROCHROMIC POLYMERS UNIVERSITY OF WASHINGTON (US) 2005-09-15 WO disclosed