Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934311 | 0.96 | MAPK8 (0.48) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL2721878 | 0.88 | MAPK8 (0.44) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL2931696 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TDP1MAPTGAAPKM | |
| SCHEMBL4236082 | 0.84 | MAPK8 (0.46) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL182627 | 0.83 | CCR2 (0.46) | ALDH1A1MAPTGAAPKMKDM4E | |
| SCHEMBL4236086 | 0.81 | MAPK8 (0.43) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL182807 | 0.80 | MAPK8 (0.57) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL3363334 | 0.77 | MAPK8 (0.53) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL34462088 | 0.75 | MAPK8 (0.52) | MAPK8ALDH1A1TDP1ARMAPT | |
| SCHEMBL2930130 | 0.73 | TSHR (0.48) | ALDH1A1TDP1MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465962-B1 | ELECTROCHROMIC POLYMERS AND POLYMER ELECTROCHROMIC DEVICES | UNIV FLORIDA (US) | 2012-01-04 | — | — | EP | disclosed |
| US-20100124702-A1 | High Energy Composite Cathodes for Lithium Ion Batteries | PHYSICAL SCIENCES, INC. (US) | 2010-05-20 | — | — | US | disclosed |
| US-20100124702-A1 | High Energy Composite Cathodes for Lithium Ion Batteries | PHYSICAL SCIENCES, INC. (US) | 2010-05-20 | — | — | US | disclosed |
| EP-1461341-B1 | PROCESS FOR PREPARING A HETEROAROMATIC COMPOUND SUBSTITUTED WITH ONE OR MORE ETHER GROUPS | AGFA GEVAERT (BE) | 2010-01-27 | — | — | EP | disclosed |
| US-6734312-B2 | CONDENSING HYDROXY- GROUP OF A COMPOUND HAVING HETEROAROMATIC NUCLEUS, WITH AN ALCOHOL CONTAINING ONE OR MORE PRIMARY OR SECONDARY ALCOHOL GROUPS, OPTIONALLY USING THE REDOX COUPLE OF A TRIARYL- OR TRIALKYLPHOSPHINE AND AN AZODIOXO-COMPOUND | AGFA-GEVAERT (BE) | 2004-05-11 | — | — | US | disclosed |
| US-20030162958-A1 | Process for preparing a compound containing a heteroaromatic group with one or more ether substituents | AGFA-GEVAERT (BE) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162958-A1 | Process for preparing a compound containing a heteroaromatic group with one or more ether substituents | ADH1C, ADH1A, CYP2E1 | MAPK8 2292/4885ALDH1A1 500/4885TDP1 826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.