Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 4/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | AR | P10275 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.70 |
| ▸ | CYP17A1 | P05093 | 10/20 | 0.66 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.66 |
| ▸ | G6PD | P11413 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GUSB | P08236 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333841 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL1418667 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL29934843 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL10301223 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL1418669 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL1419890 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL29934586 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| SCHEMBL29934837 | 1.00 | SHBG (0.70) | SHBGSERPINA6ESR1ARESR2 | |
| Sulfuric Acid SCHEMBL22717101 | 0.94 | SHBG (0.63) | SHBGSERPINA6ESR1ARESR2 | |
| Sulfuric Acid SCHEMBL22717128 | 0.94 | SHBG (0.63) | SHBGSERPINA6ESR1ARESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | SHBG 595/4885SERPINA6 409/4885ESR1 846/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | SHBG 1022/4885SERPINA6 276/4885ESR1 801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.