Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GBA1 | P04062 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3143577 | 0.81 | NPSR1 (0.70) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL10816772 | 0.78 | CA12 (0.73) | ALDH1A1LMNASMN1; SMN2KDM4EPKM | |
| SCHEMBL12640164 | 0.78 | ALDH1A1 (0.62) | ALDH1A1LMNASMN1; SMN2KDM4EPKM | |
| SCHEMBL301743 | 0.77 | ALDH1A1 (0.67) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL8349568 | 0.76 | ALDH1A1 (0.79) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL8851813 | 0.76 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL3363317 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| Hydrochloric Acid SCHEMBL7530847 | 0.75 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL27276998 | 0.75 | ALDH1A1 (0.64) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E | |
| SCHEMBL11324198 | 0.74 | MMP1 (0.54) | ALDH1A1LMNASMN1; SMN2KEAP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104418822-B | Compound with xanthine oxidase inhibitory activity and application thereof | 南京华威医药科技开发有限公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-104418822-A | Compound with xanthine oxidase inhibition activity, and use thereof | NANJING HUAWE MEDICAL TECHNOLOGY DEV CO LTD | 2015-03-18 | — | — | CN | disclosed |
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20050261332-A1 | Sulfonamides and uses thereof | ELIXIR PHARMACEUTICALS, INC. | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | ALDH1A1 2240/4885LMNA 692/4885SMN1; SMN2 862/4885 |
| US-20050261332-A1 | Sulfonamides and uses thereof | GLS2, STS, ABAT | ALDH1A1 471/4885LMNA 1603/4885SMN1; SMN2 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.