Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363120 | 0.77 | KDM4E (0.42) | GAAL3MBTL1 | |
| SCHEMBL30958030 | 0.72 | TACR2 (0.40) | GAATDP1L3MBTL1 | |
| SCHEMBL3363464 | 0.72 | CA12 (0.37) | HTR2AHTR2CGAATDP1L3MBTL1 | |
| SCHEMBL3364136 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL5644897 | 0.70 | CLCN2 (0.38) | HTR2AHTR2CGAATDP1L3MBTL1 | |
| SCHEMBL3366444 | 0.69 | ESR2 (0.33) | — | |
| SCHEMBL275497 | 0.68 | ERN1 (0.42) | HTR2AHTR2CGAATDP1 | |
| SCHEMBL31395445 | 0.68 | ERN1 (0.42) | HTR2AHTR2CGAATDP1 | |
| SCHEMBL31162886 | 0.66 | ALOX5AP (0.34) | HTR2AHTR2CGAATDP1L3MBTL1 | |
| SCHEMBL16974798 | 0.65 | DRD1 (0.37) | GAATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996590-B1 | SPIROINDOLINONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-10-06 | — | — | EP | disclosed |