Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992212 | 0.79 | MLYCD (0.49) | — | |
| SCHEMBL1445463 | 0.76 | MLYCD (0.36) | — | |
| SCHEMBL2991724 | 0.76 | MLYCD (0.36) | — | |
| SCHEMBL31078390 | 0.73 | ALDH1A1 (0.34) | TRPM5FFAR2 | |
| SCHEMBL9572166 | 0.73 | TRPM5 (0.33) | TRPM5FFAR2 | |
| SCHEMBL2988611 | 0.73 | PSEN1 (0.35) | — | |
| SCHEMBL22511316 | 0.71 | TRPM5 (0.32) | TRPM5FFAR2 | |
| SCHEMBL743585 | 0.71 | NOS1 (0.44) | TRPM5 | |
| Hydrochloric Acid SCHEMBL16416235 | 0.70 | NOS1 (0.43) | TRPM5FFAR2 | |
| Thiophene SCHEMBL2988236 | 0.69 | MLYCD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123997-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010123997-A1 | CARBACEPHEM BETA-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010030811-A2 | CARBACEPHEM β-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |
| WO-2010030811-A2 | CARBACEPHEM β-LACTAM ANTIBIOTICS | ACHAOGEN, INC. (US) | 2010-03-18 | — | — | WO | disclosed |