Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 2/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426211 | 0.86 | DAO (0.55) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9545145 | 0.77 | KDM4E (0.44) | DAOKDM4EALDH1A1GPR84 | |
| SCHEMBL9389006 | 0.77 | DAO (0.54) | DAODDO | |
| SCHEMBL3360284 | 0.75 | GRIN2D (0.60) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3422204 | 0.74 | DAO (0.49) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7030237 | 0.73 | DAO (0.41) | DAOKDM4EALDH1A1MAPTGPR84 | |
| SCHEMBL3424330 | 0.71 | ADRA2A (0.44) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3422531 | 0.71 | DAO (0.51) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1071125 | 0.71 | GPR84 (0.44) | DAOGPR84 | |
| SCHEMBL31171910 | 0.70 | EIF4A3 (0.43) | DAOKDM4EALDH1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |