Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10276952 | 0.83 | CLCN2 (0.43) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL17844023 | 0.79 | TSHR (0.49) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL8114342 | 0.77 | CLCN2 (0.42) | CLCN2GABRA1GABRB2TSHRHTT | |
| SCHEMBL3173852 | 0.77 | GABRA1 (0.44) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL2935940 | 0.76 | GABRA1 (0.48) | CLCN2GABRA1GABRB2TSHRF2R | |
| SCHEMBL29532527 | 0.76 | CLCN2 (0.41) | CLCN2GABRA1GABRB2TSHRF2R | |
| Benzene SCHEMBL28132336 | 0.76 | LMNA (0.53) | CLCN2TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL390944 | 0.76 | LMNA (0.53) | CLCN2TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL28629683 | 0.75 | SLC6A2 (0.49) | GSK3BHTTALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL3362502 | 0.74 | HCRTR1 (0.57) | TSHRHTTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |