Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362969 | 0.86 | CRHR1 (0.46) | CRHR1CHRM3MCHR1 | |
| SCHEMBL4699539 | 0.85 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3368609 | 0.81 | KDM4E (0.45) | CRHR1 | |
| SCHEMBL3367997 | 0.81 | CRHR1 (0.44) | CRHR1 | |
| SCHEMBL3366121 | 0.79 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3362477 | 0.78 | CRHR1 (0.47) | CRHR1 | |
| SCHEMBL3364228 | 0.78 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL3364735 | 0.77 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3367593 | 0.77 | CRHR1 (0.44) | CRHR1CHRM3 | |
| SCHEMBL3362470 | 0.77 | CRHR1 (0.53) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | claimed |