Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | ALPL | P05186 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MARS1 | P56192 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3367673 | 0.91 | S1PR4 (0.38) | CRHR1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL3367593 | 0.88 | CRHR1 (0.44) | CRHR1CNR1KDM4EALDH1A1GAA | |
| SCHEMBL3364763 | 0.87 | CRHR1 (0.44) | CRHR1CNR1MARS1 | |
| SCHEMBL3367997 | 0.86 | CRHR1 (0.44) | CRHR1ALPLKDM4EALDH1A1GAA | |
| SCHEMBL3368609 | 0.84 | KDM4E (0.45) | CRHR1CNR1ALPLKDM4ECNR2 | |
| SCHEMBL3366121 | 0.82 | CRHR1 (0.48) | CRHR1 | |
| SCHEMBL3364735 | 0.82 | CRHR1 (0.51) | CRHR1 | |
| SCHEMBL3367441 | 0.82 | CRHR1 (0.47) | CRHR1CNR1ALPLKDM4EALDH1A1 | |
| SCHEMBL3362477 | 0.81 | CRHR1 (0.47) | CRHR1KDM4E | |
| SCHEMBL3364610 | 0.80 | CRHR1 (0.49) | CRHR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656353-B1 | GABANERGIC MODULATORS | HOFFMANN LA ROCHE (CH) | 2010-01-27 | — | — | EP | claimed |