Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 5/20 | 0.38 |
| ▸ | CCNK | O75909 | 8/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 8/20 | 0.38 |
| ▸ | CDK7 | P50613 | 7/20 | 0.38 |
| ▸ | CCNH | P51946 | 7/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 6/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CDK9 | P50750 | 3/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366225 | 0.85 | HSP90AB1 (0.44) | CYP11B1CYP11B2EGLN2CCNKCDK12 | |
| SCHEMBL3361910 | 0.83 | CYP11B2 (0.42) | CYP11B1CYP11B2EGLN2 | |
| SCHEMBL3364557 | 0.82 | CSNK1A1 (0.43) | CYP11B1CYP11B2EGLN2 | |
| SCHEMBL21178905 | 0.78 | CCNK (0.60) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL30007191 | 0.78 | CCNK (0.60) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL25552036 | 0.75 | PDK1 (0.41) | CYP11B1CYP11B2EGLN2SLC22A12NSD2 | |
| SCHEMBL30037562 | 0.75 | PDK1 (0.41) | CYP11B1CYP11B2EGLN2SLC22A12NSD2 | |
| SCHEMBL3813659 | 0.72 | AR (0.39) | LRRK2 | |
| SCHEMBL25519458 | 0.72 | EGLN2 (0.41) | CYP11B1CYP11B2EGLN2TRPV4SLC22A12 | |
| SCHEMBL21184412 | 0.71 | DGAT1 (0.38) | CCNKCDK12CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |