Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364583 | 0.77 | CA1 (0.46) | LMNAGAAKMT2ATSHRHTT | |
| SCHEMBL3363688 | 0.74 | CCNB2 (0.55) | LMNAGAAALDH1A1LTA4H | |
| SCHEMBL4350378 | 0.73 | ALDH1A1 (0.47) | LMNAGAAKMT2ATSHRHTT | |
| SCHEMBL3366339 | 0.73 | DRD1 (0.45) | LMNAGAAKMT2AHTTHPGD | |
| SCHEMBL3362504 | 0.73 | ALDH1A1 (0.44) | LMNAGAAKMT2AHTTALDH1A1 | |
| SCHEMBL3366374 | 0.73 | IRAK4 (0.42) | LMNAGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL1676646 | 0.72 | LTA4H (0.53) | LMNAGAAKMT2ATSHRCTNNB1 | |
| SCHEMBL8776759 | 0.72 | RIPK1 (0.53) | LMNAGAAKMT2ATSHRHTT | |
| SCHEMBL11176072 | 0.72 | DPP4 (0.47) | LMNAGAAKMT2ATSHRHTT | |
| SCHEMBL278540 | 0.72 | RIPK1 (0.53) | LMNAGAAKMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |