Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10438873 | 0.98 | LMNA (0.61) | LMNAL3MBTL1ACHEMAOBCYP3A4 | |
| SCHEMBL9338212 | 0.82 | LMNA (0.52) | LMNAL3MBTL1ACHEMAOBCYP3A4 | |
| SCHEMBL28599111 | 0.81 | MEN1 (0.46) | LMNAMAOBTSHRALDH1A1CES2 | |
| SCHEMBL27406073 | 0.81 | HPGD (0.46) | LMNAMAOBCYP3A4TSHRCES2 | |
| SCHEMBL8586307 | 0.80 | CES2 (0.52) | LMNACES2CES1SMN1; SMN2MAPT | |
| SCHEMBL6200881 | 0.80 | MEN1 (0.44) | LMNACYP3A4TSHRALDH1A1MAPT | |
| SCHEMBL11245363 | 0.80 | ELANE (0.44) | LMNAL3MBTL1CYP3A4TSHRALDH1A1 | |
| SCHEMBL156135 | 0.78 | HPGD (0.47) | LMNAMAOBCYP3A4TSHRCES2 | |
| SCHEMBL7869484 | 0.78 | MAPT (0.61) | LMNAL3MBTL1MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL9510016 | 0.78 | TDP1 (0.44) | LMNACYP3A4TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666566-B2 | Electrophotographic toner and method of preparing the toner | RICOH COMPANY, LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20050196691-A1 | Electrophotographic toner and method of preparing the toner | RICOH COMPANY, LTD. (JP) | 2005-09-08 | — | — | US | disclosed |