Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 7/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200881 | 0.82 | MEN1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL10438873 | 0.82 | LMNA (0.61) | CES2CES1CA1CA2CA9 | |
| SCHEMBL3364623 | 0.80 | LMNA (0.59) | CES2CES1CA1CA2CA9 | |
| SCHEMBL3725791 | 0.80 | MAOB (0.43) | CES2CES1CA1CA2SMN1; SMN2 | |
| SCHEMBL21612930 | 0.80 | MEN1 (0.47) | CES2CES1CA1CA2CA9 | |
| SCHEMBL156135 | 0.80 | HPGD (0.47) | CES2CES1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9510016 | 0.80 | TDP1 (0.44) | MAPTPARP10RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7869484 | 0.80 | MAPT (0.61) | MAPTRAB9ASMN1; SMN2LMNAKMT2A | |
| Benzene SCHEMBL9407301 | 0.79 | ELANE (0.45) | CES2CES1MAPTBACE1LMNA | |
| SCHEMBL247575 | 0.79 | ELANE (0.45) | CES2CES1MAPTBACE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4251608-A1 | ANTICHOLINERGIC AGENTS | Rezubio Pharmaceuticals Co., Ltd (CN) | 2023-10-04 | — | — | EP | disclosed |
| CN-115135152-A | 1, 5-diphenylpyrazolyl-3-oxyalkyl acids and 1-phenyl-5-thienylpyrazolyl-3-oxyalkyl acids and their use for controlling undesired vegetation | 拜耳公司 | 2022-09-30 | — | — | CN | disclosed |
| WO-2022111500-A1 | ANTICHOLINERGIC AGENTS | REZUBIO PHARMACEUTICALS CO., LTD (CN) | 2022-06-02 | — | — | WO | disclosed |
| CN-114071999-A | 1-phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling undesired vegetation | 拜耳公司 | 2022-02-18 | — | — | CN | disclosed |
| EP-2595952-B1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT LTD (IN) | 2020-11-18 | — | — | EP | disclosed |
| EP-2595952-A1 | AGONISTS OF GPR40 | Connexios Life Sciences Pvt. Ltd. (IN) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012011125-A1 | AGONISTS OF GPR40 | CONNEXIOS LIFE SCIENCES PVT. LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |
| WO-1998031697-A1 | ARYL C-GLYCOSIDE COMPOUNDS AND SULFATED ESTERS THEREOF | SANKYO COMPANY, LIMITED (JP) | 1998-07-23 | — | — | WO | disclosed |