Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26126123 | 0.80 | ELANE (0.70) | MAPTL3MBTL1GAASTSSMN1; SMN2 | |
| SCHEMBL6200881 | 0.80 | MEN1 (0.44) | MAPTGAALMNAKMT2AALDH1A1 | |
| SCHEMBL10438873 | 0.80 | LMNA (0.61) | MAPTHPGDL3MBTL1LMNAMAOB | |
| SCHEMBL8586307 | 0.80 | CES2 (0.52) | MAPTRAB9ALMNANPSR1SMN1; SMN2 | |
| SCHEMBL10460891 | 0.78 | MAPT (0.61) | MAPTHPGDRAB9AL3MBTL1GAA | |
| SCHEMBL9510016 | 0.78 | TDP1 (0.44) | MAPTHPGDRAB9AGAALMNA | |
| SCHEMBL3725791 | 0.78 | MAOB (0.43) | GAALMNAMAOBSMN1; SMN2ALDH1A1 | |
| SCHEMBL21612930 | 0.78 | MEN1 (0.47) | MAPTRAB9ALMNANPSR1MAOB | |
| SCHEMBL156135 | 0.78 | HPGD (0.47) | MAPTHPGDLMNAMAOBSMN1; SMN2 | |
| SCHEMBL3364623 | 0.78 | LMNA (0.59) | MAPTHPGDL3MBTL1LMNAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316493-B1 | FOR THERAPY OF MALARIA | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2001-11-13 | — | — | US | disclosed |