Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3037922 | 0.84 | KMO (0.48) | KMOCYP1A2CYP3A4HSD17B10TSHR | |
| SCHEMBL27964563 | 0.83 | CYP1A2 (0.69) | KMOCYP1A2CYP3A4HSD17B10TSHR | |
| SCHEMBL25428915 | 0.80 | KMO (0.60) | KMOCYP1A2CYP3A4HSD17B10TSHR | |
| SCHEMBL935401 | 0.80 | KMO (0.60) | KMOCYP1A2CYP3A4HSD17B10TSHR | |
| SCHEMBL2350242 | 0.77 | NPC1 (0.47) | KMOTDP1TGFBR1KDM4E | |
| SCHEMBL447060 | 0.77 | CYP19A1 (0.47) | KMOCYP1A2CYP3A4ALOX15TDP1 | |
| SCHEMBL21058751 | 0.77 | ACP1 (0.47) | KMOCYP1A2CYP3A4ALDH1A1MEN1 | |
| SCHEMBL18333 | 0.76 | CTSK (0.56) | KMOCYP1A2CYP3A4HSD17B10TSHR | |
| SCHEMBL3248212 | 0.75 | NOTUM (0.44) | KMOCYP1A2CYP3A4HSD11B1ACP1 | |
| SCHEMBL802294 | 0.74 | MEN1 (0.62) | KMOHSD17B10TDP1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |