Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | STK10 | O94804 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 3/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396037 | 0.86 | FFAR1 (0.46) | FFAR1 | |
| SCHEMBL13426115 | 0.84 | SOD1 (0.49) | — | |
| SCHEMBL3399321 | 0.83 | FFAR1 (0.42) | GRM5FFAR1PRMT5WDR77MEN1 | |
| SCHEMBL3397786 | 0.81 | SCN9A (0.44) | GRM5FFAR1PRMT5WDR77 | |
| SCHEMBL13426010 | 0.79 | FFAR1 (0.48) | FFAR1HSD17B10STK10SLKMAPT | |
| SCHEMBL13426151 | 0.76 | CYP1A2 (0.47) | HSD17B10KDM4EHTR7LMNAMAPK1 | |
| SCHEMBL421390 | 0.74 | LMNA (0.61) | FFAR1KDM4ELMNAMAPK1HTT | |
| SCHEMBL1528375 | 0.73 | HSD17B10 (0.53) | FFAR1HSD17B10KDM4EMAPTSYK | |
| SCHEMBL16841261 | 0.73 | RAB9A (0.59) | HSD17B10KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL27768176 | 0.72 | AR (0.46) | HSD17B10KDM4EMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |