SCHEMBL3365709

SCHEMBL3365709

O=Cc1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)cc3)s2)s1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.74
MAPT P10636 4/20 0.48
DPP4 P27487 1/20 0.40
CYP2E1 P05181 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2A6 P11509 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2B6 P20813 1/20 0.38
CYP2C19 P33261 1/20 0.38
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
PRF1 P14222 1/20 0.35
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3365447 0.88 APP (0.59) APPMAPTDPP4CYP2E1CYP3A4
SCHEMBL3364925 0.88 APP (0.54) APPMAPTCYP2A6CA12CA1
SCHEMBL14018333 0.86 APP (0.52) APPMAPTCYP3A4CYP2C9CYP2C19
SCHEMBL2592315 0.86 APP (1.00) APPMAPTDPP4CYP2E1CYP3A4
SCHEMBL14713496 0.86 APP (1.00) APPMAPTDPP4CYP2E1CYP3A4
SCHEMBL13854575 0.84 APP (0.51) APPMAPTCYP3A4CYP2C9CYP2C19
SCHEMBL13020735 0.84 APP (0.47) APPMAPTCYP2E1CYP3A4CYP2A6
SCHEMBL10109321 0.83 APP (0.50) APPMAPTCYP3A4CYP2C9CYP2C19
SCHEMBL13125857 0.83 APP (0.50) APPMAPTCYP3A4CYP2C9CYP2C19
SCHEMBL18194049 0.83 APP (0.46) APPMAPTCYP2E1CYP3A4CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 APP 2553/4885MAPT 4399/4885DPP4 3576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.