SCHEMBL3365447

SCHEMBL3365447

O=Cc1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4cccc5ccccc45)s3)s2)s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.59
DPP4 P27487 1/20 0.40
MAPT P10636 4/20 0.38
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
SIGMAR1 Q99720 4/20 0.33
CYP2A6 P11509 2/20 0.33
CYP2E1 P05181 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17720361 0.91 APP (0.48) APPMAPTKDM4EHPGDMEN1
SCHEMBL3365709 0.88 APP (0.74) APPDPP4MAPTKDM4EHPGD
SCHEMBL8994816 0.87 SIGMAR1 (0.41) APPMAPTKDM4EKMT2ASIGMAR1
SCHEMBL3364398 0.84 APP (0.70) APPDPP4MAPTKDM4EHPGD
SCHEMBL3368635 0.82 SIGMAR1 (0.36) APPMAPTKDM4EHPGDMEN1
SCHEMBL7133882 0.82 SIGMAR1 (0.39) APPSIGMAR1CYP3A4CYP2C9CYP2C19
SCHEMBL3364204 0.81 MAPT (0.66) APPMAPTKDM4EHPGDMEN1
SCHEMBL8075913 0.80 SIGMAR1 (0.44) KDM4EHPGDSIGMAR1CYP2A6CYP3A4
SCHEMBL27744329 0.78 APP (0.41) APPMAPTSIGMAR1
SCHEMBL3364925 0.75 APP (0.54) APPMAPTSIGMAR1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8183393-B2 Dye compound and dye-sensitized solar cell ACADEMIA SINICA (TW) 2012-05-22 US disclosed
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL ACADEMIA SINICA (TW) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076205-A1 DYE COMPOUND AND DYE-SENSITIZED SOLAR CELL CRY1, DSG1, CRY2 APP 2553/4885DPP4 3576/4885MAPT 4399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.