Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28035808 | 0.97 | KDM4E (0.44) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL1258379 | 0.97 | CA2 (0.42) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL2914797 | 0.94 | ALDH1A1 (0.44) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL2918689 | 0.90 | CXCR4 (0.41) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL2010175 | 0.90 | CA2 (0.36) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| Piperazine SCHEMBL28198825 | 0.90 | CXCR4 (0.44) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL5030028 | 0.89 | ALDH1A1 (0.47) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL28441176 | 0.88 | CXCR4 (0.44) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL3769647 | 0.87 | CXCR4 (0.42) | CA2CHKAKDM4ESMN1; SMN2USP2 | |
| SCHEMBL1997368 | 0.87 | CXCR4 (0.42) | CA2CHKAKDM4ESMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240010913-A1 | RED FLUORESCENT SENSOR COMPOUNDS FOR THE DETECTION OF METAL IONS | FEMTONICS KFT. (HU) | 2024-01-11 | — | — | US | claimed |
| CN-115835911-A | Imidazo [1,2-a ] pyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-115417858-A | Intracellular self-assembly ALK degradation agent based on bioorthogonal strategy and preparation method and application thereof | 中国药科大学 | 2022-12-02 | — | — | CN | claimed |
| WO-2022118054-A1 | RED FLUORESCENT SENSOR COMPOUNDS FOR THE DETECTION OF METAL IONS | FEMTONICS KFT. (HU) | 2022-06-09 | — | — | WO | claimed |
| CN-112673003-A | Novel pyrrolidine amine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2021-04-16 | — | — | CN | claimed |
| CN-112341436-A | Benzocarbazole proteolysis targeted chimeric molecule based on targeted inhibition and ALK degradation, preparation method and application | 中国药科大学 | 2021-02-09 | — | — | CN | claimed |
| WO-2020228635-A1 | EGFR KINASE INHIBITOR AND APPLICATION THEREOF IN PREPARING ANTI-CANCER DRUG | 浙江大学 | 2020-11-19 | — | — | WO | claimed |
| CN-110965374-A | Environment-friendly chlorine-resistant color fixing agent and preparation method thereof | 王秋平 | 2020-04-07 | — | — | CN | claimed |
| US-10465015-B2 | Lentinan extraction process from mushrooms using ionic liquid | K Hughes & Co., Ltd. (GB) | 2019-11-05 | — | — | US | claimed |
| CN-108218026-B | A method of processing waste water containing piperidine alcohols simultaneously recycles piperidine alcohols | 杭州九清科技有限公司 | 2019-03-05 | — | — | CN | claimed |
| WO-2005087714-A2 | METHODS OF TREATMENT OF AMYLOIDOSIS USING BI-CYCLIC ASPARTYL PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| WO-2005087215-A1 | SUBSTITUTED UREA AND CARBAMATE, PHENACYL-2-HYDROXY-3-DIAMINOALKANE, AND BENZAMIDE-2-HYDROXY-3-DIAMINOALKANE ASPARTYL-PROTEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN, INC. | 2005-07-28 | — | — | US | claimed |
| US-6864254-B1 | Inhibitor for 20-hete-yielding enzyme | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2005-03-08 | — | — | US | claimed |
| EP-1480954-A1 | VANILLOID RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2004-12-01 | — | — | EP | claimed |
| WO-2003068749-A1 | VANILLOID RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2003-08-21 | — | — | WO | claimed |
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | claimed |
| EP-0191045-B1 | USE OF 4-(ISOXAZOLYL)-THIAZOLE-2-OXAMIC ACID DERIVATIVES | ZAMBON S.p.A. (IT) | 1989-12-20 | — | — | EP | claimed |
| US-4774246-A | 6,8-DIFLUORO-4-OXO-3-CARBOXYLIC ACID DERIVATIVES | ABBOTT LABORATORIES (US) | 1988-09-27 | — | — | US | claimed |
| EP-0071892-B1 | PHOSPHOLIPID DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION OF THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-10-23 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165049-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | CA2 908/4885CHKA 1815/4885KDM4E 4218/4885 |
| US-20240010913-A1 | RED FLUORESCENT SENSOR COMPOUNDS FOR THE DETECTION OF METAL IONS | SLC30A6, SLC30A7, SLC39A14 | CA2 18/4885CHKA 4275/4885KDM4E 3882/4885 |
| US-10465015-B2 | Lentinan extraction process from mushrooms using ionic liquid | MGAM, LMAN1, PIM1 | CA2 3307/4885CHKA 3859/4885KDM4E 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.