Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758519 | 1.00 | ELANE (0.46) | ELANENPC1RAB9AGSK3BALDH1A1 | |
| SCHEMBL10671873 | 0.83 | ELANE (0.43) | ELANENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL11771242 | 0.83 | ALDH1A1 (0.47) | ELANENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL29035082 | 0.82 | NPC1 (0.44) | ELANENPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL29573780 | 0.80 | F2R (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2360603 | 0.80 | F2R (0.49) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL11893584 | 0.79 | PRNP (0.50) | GSK3BALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8445974 | 0.77 | KDM4E (0.54) | NPC1RAB9AGSK3BALDH1A1MEN1 | |
| SCHEMBL235265 | 0.76 | CES2 (0.58) | ELANEGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL28629683 | 0.76 | SLC6A2 (0.49) | ELANENPC1RAB9AGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |