Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.67 |
| ▸ | BACE1 | P56817 | 9/20 | 0.67 |
| ▸ | BCHE | P06276 | 6/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5121429 | 0.90 | BCHE (0.64) | ACHEBACE1BCHECCR3 | |
| SCHEMBL5091801 | 0.82 | ACHE (0.62) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL41919 | 0.82 | ACHE (0.62) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL14636487 | 0.80 | ACHE (0.58) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL14636486 | 0.80 | ACHE (0.58) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL3367341 | 0.80 | CYP2D6 (0.60) | ACHEBACE1BCHE | |
| SCHEMBL156315 | 0.79 | ACHE (1.00) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL8315434 | 0.79 | ACHE (0.71) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL22872251 | 0.79 | ACHE (0.66) | ACHEBACE1BCHECCR3SIGMAR1 | |
| SCHEMBL5909546 | 0.78 | CCR3 (0.63) | ACHEBCHECCR3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730115-B1 | 5-AMINOALKYLPYRAZOLE DERIVATIVES AS PESTICIDAL AGENTS | MERIAL LTD (US) | 2010-06-09 | — | — | EP | disclosed |
| US-7659288-B2 | 5-[N-Methyl-N-(phthalimidomethyl)amino]-1-(2,6-dichloro-4-trifluoromethylphenyl)-3-cyano-4-trifluoromethylsulfinylpyrazole; used in oral form so as to prevent the possible contamination of humans or the surrounding environment; used in lower dose | MERIAL LIMITED (US) | 2010-02-09 | — | — | US | disclosed |
| US-20070149575-A1 | 5-Aminoalkylpyrazole derivatives as pesticidal agents | MERIAL, INC. | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149575-A1 | 5-Aminoalkylpyrazole derivatives as pesticidal agents | DDT, AASDHPPT, ACHE | ACHE 3/4885BACE1 2214/4885BCHE 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.