Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL243876 | 0.95 | — | — | |
| Potassium Ion SCHEMBL2059770 | 0.90 | — | — | |
| Water SCHEMBL220755 | 0.90 | — | — | |
| SCHEMBL17785148 | 0.90 | — | — | |
| Fluoride Ion SCHEMBL4753071 | 0.89 | — | — | |
| SCHEMBL35478 | 0.89 | — | — | |
| Fluoride Ion SCHEMBL3291524 | 0.89 | — | — | |
| Fluoride Ion SCHEMBL4752879 | 0.89 | — | — | |
| SCHEMBL97357 | 0.89 | — | — | |
| SCHEMBL449484 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010144972-A1 | A CATALYTIC MATERIAL, METHOD OF MANUFACTURE AND METHOD OF USE | NEWSQUARE TRADING LIMITED (CN) | 2010-12-23 | — | — | WO | disclosed |