Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Fluoride Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL3291524 | 1.00 | — | — | |
| Fluoride Ion SCHEMBL13387481 | 0.94 | — | — | |
| Fluoride Ion SCHEMBL892977 | 0.94 | — | — | |
| Fluoride Ion SCHEMBL9107779 | 0.94 | — | — | |
| SCHEMBL9126752 | 0.94 | — | — | |
| SCHEMBL9398161 | 0.94 | — | — | |
| SCHEMBL26885 | 0.94 | — | — | |
| SCHEMBL9701931 | 0.94 | — | — | |
| SCHEMBL17236 | 0.94 | — | — | |
| Fluoride Ion SCHEMBL2475572 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9320692-B2 | Tooth fluoridating and remineralizing compositions and methods, based on nanoaggregate formation | ADA FOUNDATION (US) | 2016-04-26 | — | — | US | claimed |
| WO-2012119155-A1 | ANTIMICROBIAL COMPOSITIONS FOR TOOTH FLUORIDATION AND REMINERALIZATION | AMERICAN DENTAL ASSOCIATION FOUNDATION (US) | 2012-09-07 | — | — | WO | claimed |
| WO-2008147997-A1 | TOOTH FLUORIDATING AND REMINERALIZING COMPOSITIONS AND METHODS, BASED ON NANOAGGREGATE FORMATION | ADA FOUNDATION (US) | 2008-12-04 | — | — | WO | claimed |
| US-20080292565-A1 | TOOTH FLUORIDATING AND REMINERALIZING COMPOSITIONS AND METHODS, BASED ON NANOAGGREGATE FORMATION | ADA FOUNDATION (US) | 2008-11-27 | — | — | US | claimed |
| CN-102413682-A | Pesticidal compositions exhibiting enhanced activity and process for preparing same | DOW AGROSCIENCES LLC | 2012-04-11 | — | — | CN | disclosed |
| CN-102413690-A | Pesticide composition comprising spinosad, metal and protein material | DOW AGROSCIENCES LLC | 2012-04-11 | — | — | CN | disclosed |
| CN-102413688-A | Pesticide composition comprising a macrolide, a polymer and a proteinaceous material | DOW AGROSCIENCES LLC | 2012-04-11 | — | — | CN | disclosed |