Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424728 | 0.76 | TSHR (0.73) | TSHRLMNATYRCYP1A2ALDH1A1 | |
| SCHEMBL3365770 | 0.76 | CYP2A6 (0.44) | CYP1A2ALDH1A1CA1CA2CA9 | |
| SCHEMBL4926591 | 0.76 | TSHR (0.50) | TSHRLMNATYRTP53CYP1A2 | |
| SCHEMBL3424511 | 0.74 | HSD17B10 (0.46) | TSHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL43060 | 0.74 | EPHX2 (0.56) | TSHRLMNATYRTP53CYP1A2 | |
| SCHEMBL7070033 | 0.74 | CES2 (0.46) | TSHRCYP1A2ALDH1A1HDAC1SRD5A2 | |
| SCHEMBL3364629 | 0.74 | KCNN4 (0.43) | LMNAALDH1A1MEN1KMT2AHTT | |
| SCHEMBL3360355 | 0.73 | ALDH1A1 (0.52) | TSHRLMNATP53CYP1A2ALDH1A1 | |
| SCHEMBL3362932 | 0.73 | PLK1 (0.41) | TSHRLMNATP53ALDH1A1MEN1 | |
| SCHEMBL11210257 | 0.71 | TSHR (0.58) | TSHRLMNATYRCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |