Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.43 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | NOS2 | P35228 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366217 | 0.81 | KCNH2 (0.52) | NOS3NOS1NOS2KDM4EMEN1 | |
| SCHEMBL3361839 | 0.81 | GRM5 (0.43) | EGLN2CDK2GRM5 | |
| SCHEMBL3366055 | 0.79 | NOS3 (0.52) | NOS3NOS1NOS2KDM4EMEN1 | |
| SCHEMBL3397985 | 0.76 | DYRK1A (0.54) | DYRK1AGSK3BEGLN2AAK1CDC7 | |
| SCHEMBL29432635 | 0.76 | DYRK1A (0.54) | DYRK1AGSK3BEGLN2AAK1CDC7 | |
| SCHEMBL23809618 | 0.73 | DYRK1A (0.45) | NOS3NOS1NOS2KDM4EMEN1 | |
| SCHEMBL18998664 | 0.73 | CLK4 (0.59) | DYRK1AGSK3BCDC7CDK2GRM5 | |
| SCHEMBL312451 | 0.73 | — | — | |
| SCHEMBL31294130 | 0.73 | — | — | |
| SCHEMBL3360845 | 0.72 | EGLN2 (0.48) | DYRK1AGSK3BEGLN2METAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |