Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 6/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360845 | 0.82 | EGLN2 (0.48) | KCNH2EGLN2DYRK1AGSK3BCDC7 | |
| SCHEMBL3366423 | 0.81 | NOS3 (0.43) | KCNH2EGLN2DYRK1AGSK3BCDC7 | |
| SCHEMBL3362974 | 0.78 | S1PR1 (0.47) | DYRK1AGSK3BCDC7CDK2NOS3 | |
| SCHEMBL3397985 | 0.77 | DYRK1A (0.54) | EGLN2DYRK1AGSK3BCDC7CDK2 | |
| SCHEMBL29432635 | 0.77 | DYRK1A (0.54) | EGLN2DYRK1AGSK3BCDC7CDK2 | |
| SCHEMBL13425430 | 0.75 | MAP3K14 (0.59) | KCNH2EGLN2DYRK1AGSK3BCDC7 | |
| SCHEMBL7634772 | 0.75 | ALDH1A1 (0.48) | EGLN2CYP11B1CYP11B2S1PR1 | |
| SCHEMBL23809618 | 0.74 | DYRK1A (0.45) | KCNH2DYRK1AGSK3BCDC7CDK2 | |
| SCHEMBL18998664 | 0.74 | CLK4 (0.59) | DYRK1AGSK3BCDC7CDK2 | |
| SCHEMBL31294130 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |