Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | OXTR | P30559 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366735 | 1.00 | RAB9A (0.53) | RAB9AMEN1KMT2AOXTRNPC1 | |
| SCHEMBL3365642 | 0.93 | OXTR (0.54) | RAB9AMEN1KMT2AOXTRNPC1 | |
| SCHEMBL3365636 | 0.93 | OXTR (0.54) | RAB9AMEN1KMT2AOXTRNPC1 | |
| SCHEMBL3396501 | 0.90 | ALDH1A1 (0.54) | RAB9AMEN1KMT2AOXTRALDH1A1 | |
| SCHEMBL3366952 | 0.90 | ALDH1A1 (0.54) | RAB9AMEN1KMT2AOXTRALDH1A1 | |
| SCHEMBL3366955 | 0.90 | ALDH1A1 (0.54) | RAB9AMEN1KMT2AOXTRALDH1A1 | |
| SCHEMBL3366189 | 0.89 | MAPT (0.53) | MEN1KMT2AOXTRL3MBTL1ALDH1A1 | |
| SCHEMBL3366186 | 0.89 | MAPT (0.53) | MEN1KMT2AOXTRL3MBTL1ALDH1A1 | |
| SCHEMBL3369773 | 0.89 | MAPT (0.53) | MEN1KMT2AOXTRL3MBTL1ALDH1A1 | |
| SCHEMBL3367355 | 0.88 | SMN1; SMN2 (0.54) | RAB9AMEN1KMT2AOXTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |