Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366978 | 0.86 | KMT2A (0.40) | HTTTSHRKMT2ACYP2D6CYP3A4 | |
| SCHEMBL4886714 | 0.81 | PABPC1 (0.41) | POLBTSHRKMT2ALMNASMN1; SMN2 | |
| SCHEMBL3363020 | 0.81 | POLB (0.41) | TACR1TACR3HTTPOLBTSHR | |
| SCHEMBL3369033 | 0.80 | KMT2A (0.45) | POLBTSHRKMT2ACYP2D6CYP3A4 | |
| SCHEMBL7517238 | 0.78 | KMT2A (0.40) | HTTTSHRKMT2AMEN1ALDH1A1 | |
| SCHEMBL5346731 | 0.75 | TACR1 (0.43) | TACR1TACR3HTTPOLBTSHR | |
| SCHEMBL13846318 | 0.74 | CYP2D6 (0.35) | HTTTSHRKMT2ACYP2D6CYP3A4 | |
| SCHEMBL25452991 | 0.74 | KMT2A (0.46) | POLBTSHRKMT2ACYP2D6CYP3A4 | |
| SCHEMBL7521073 | 0.74 | KMT2A (0.43) | HTTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL12274081 | 0.73 | TSHR (0.47) | TSHRKMT2ACYP2D6LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284966-B1 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES | BASF SE (DE) | 2010-03-17 | — | — | EP | disclosed |
| US-7402675-B2 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-07-22 | — | — | US | disclosed |
| US-6900328-B2 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-05-31 | — | — | US | disclosed |
| US-20050043552-A1 | Process for the synthesis of amine ethers from secondary amino oxides | HAFNER ANDREAS (CH) | 2005-02-24 | — | — | US | disclosed |
| US-20030171461-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-09-11 | — | — | US | disclosed |
| EP-1284966-A2 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES | Ciba SC Holding AG (CH) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092228-A2 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043552-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CYC1, AOC2, CBR1 | TACR1 871/4885TACR3 2044/4885HTT 2391/4885 |
| US-20030171461-A1 | Process for the synthesis of amine ethers from secondary amino oxides | IL4I1, HCCS, CBR1 | TACR1 3271/4885TACR3 4003/4885HTT 3571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.