Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366978 | 0.83 | KMT2A (0.40) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL25452991 | 0.80 | KMT2A (0.46) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL4805192 | 0.80 | TSHR (0.45) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL3366770 | 0.80 | TACR1 (0.42) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL4886714 | 0.79 | PABPC1 (0.41) | KMT2ATSHRLMNAMEN1GAA | |
| SCHEMBL12274081 | 0.75 | TSHR (0.47) | KMT2ATSHRCYP2D6LMNAGAA | |
| SCHEMBL12285055 | 0.73 | TSHR (0.45) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL13474844 | 0.73 | KMT2A (0.61) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL19937304 | 0.73 | KMT2A (0.61) | KMT2ATSHRCYP2D6LMNAMEN1 | |
| SCHEMBL13846318 | 0.72 | CYP2D6 (0.35) | KMT2ATSHRCYP2D6LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284966-B1 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES | BASF SE (DE) | 2010-03-17 | — | — | EP | disclosed |
| US-7402675-B2 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-07-22 | — | — | US | disclosed |
| US-6900328-B2 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-05-31 | — | — | US | disclosed |
| US-20050043552-A1 | Process for the synthesis of amine ethers from secondary amino oxides | HAFNER ANDREAS (CH) | 2005-02-24 | — | — | US | disclosed |
| US-20030171461-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-09-11 | — | — | US | disclosed |
| EP-1284966-A2 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES | Ciba SC Holding AG (CH) | 2003-02-26 | — | — | EP | disclosed |
| WO-2001092228-A2 | PROCESS FOR THE SYNTHESIS OF AMINE ETHERS FROM SECONDARY AMINO OXIDES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050043552-A1 | Process for the synthesis of amine ethers from secondary amino oxides | CYC1, AOC2, CBR1 | KMT2A 1447/4885TSHR 831/4885CYP2D6 72/4885 |
| US-20030171461-A1 | Process for the synthesis of amine ethers from secondary amino oxides | IL4I1, HCCS, CBR1 | KMT2A 1055/4885TSHR 1905/4885CYP2D6 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.