SCHEMBL3366833

SCHEMBL3366833

Oc1ccc(C2c3ccccc3-c3ccccc32)cc1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.50
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 3/20 0.48
HPGD P15428 2/20 0.48
BCL2L1 Q07817 1/20 0.48
KDM1A O60341 2/20 0.42
PELI1 Q96FA3 1/20 0.41
BRD4 O60885 1/20 0.41
NR1I2 O75469 1/20 0.41
SMARCA2 P51531 1/20 0.41
SMARCA4 P51532 1/20 0.41
PBRM1 Q86U86 1/20 0.41
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
ALOX5 P09917 2/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
GAA P10253 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MAPT P10636 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631137 0.85 HSD17B1 (0.43) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL9461093 0.82 BACE1 (0.43) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL4640231 0.79 ALDH1A1 (0.44) ALDH1A1HSD17B10HPGDMEN1KMT2A
SCHEMBL918079 0.77 ESR1 (0.44) ALDH1A1HSD17B10HPGDHSD17B1HSD17B2
SCHEMBL17574463 0.77 KDM4E (0.42) ALDH1A1HSD17B10KDM1AMEN1KMT2A
SCHEMBL17574469 0.77 ESR2 (0.43) ALDH1A1HSD17B10MEN1KMT2AGAA
SCHEMBL17574467 0.77 JAK2 (0.43) HSD17B1HSD17B2MEN1KMT2AGAA
SCHEMBL22272290 0.75 HSD17B1 (0.48) BACE1ALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL577449 0.75 TP53 (0.49) ALDH1A1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL27372447 0.75 KDM1A (0.47) ALDH1A1HSD17B10HPGDBCL2L1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736073-A Synthesis method of 9, 9-bis (3-phenyl-4-hydroxyphenyl) fluorene 中唯炼焦技术国家工程研究中心有限责任公司 2024-03-22 CN claimed
CN-109195936-B Method for producing alcohols having fluorene skeleton 田冈化学工业株式会社 2022-02-11 CN claimed
CN-112888579-B Rubber-like composition and method for producing same 大阪瓦斯株式会社 2024-07-09 CN disclosed
CN-118251441-A Process for producing polyether nitrile 本州化学工业株式会社 2024-06-25 CN disclosed
CN-118251460-A Polycarbonate resin composition and optical lens using the same 三菱瓦斯化学株式会社 2024-06-25 CN disclosed
CN-118251442-A Process for producing polyether nitrile 本州化学工业株式会社 2024-06-25 CN disclosed
CN-118234780-A Process for producing polyether nitrile 本州化学工业株式会社 2024-06-21 CN disclosed
US-20240199924-A1 LAMINATE, RELEASE AGENT COMPOSITION, AND METHOD FOR MANUFACTURING PROCESSED SEMICONDUCTOR SUBSTRATE NISSAN CHEMICAL CORPORATION (JP) 2024-06-20 US disclosed
CN-118176235-A Thermoplastic resin and optical member 帝人株式会社 2024-06-11 CN disclosed
CN-113474685-B optical lens 帝人株式会社 2024-05-28 CN disclosed
CN-118043298-A (Hetero) aryl-substituted bisphenol compound and thermoplastic resin 罗伊特化学仪器制造公司 2024-05-14 CN disclosed
EP-1840167-B1 TRANSPARENT GEL AND CONTACT LENS COMPRISING THE SAME MENICON CO LTD (JP) 2010-10-06 EP disclosed
US-20090012205-A1 TRANSPARENT GEL AND CONTACT LENSE FROM THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-01-08 US disclosed
US-20080027244-A1 Method for Manufacturing Aromatic Dicarboxylic Acid JFE CHEMICAL CORPORATION (JP) 2008-01-31 US disclosed
EP-1840167-A1 TRANSPARENT GEL AND CONTACT LENS COMPRISING THE SAME MENICON CO., LTD. (JP) 2007-10-03 EP disclosed
EP-1138714-B1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL CO (JP) 2005-02-23 EP disclosed
EP-1138714-A2 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-10-04 EP disclosed
US-5633331-A TRANSPARENT, NONHYDROLYZING, IMPACT RESISTANT, DUCTILE THE DOW CHEMICAL COMPANY (US) 1997-05-27 US disclosed
WO-1996029366-A1 BLENDS OF DIARYL FLUORENE CARBONATE POLYMERS WITH BISPHENOL A CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
US-5486577-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027244-A1 Method for Manufacturing Aromatic Dicarboxylic Acid DDC, PAH, ALDH7A1 BACE1 4020/4885ALDH1A1 66/4885HSD17B10 47/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.