SCHEMBL577449

SCHEMBL577449

OCCOc1ccc(C2c3ccccc3-c3ccccc32)cc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.49
MAPK1 P28482 1/20 0.49
RAB9A P51151 1/20 0.49
LMNA P02545 3/20 0.46
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
HTR7 P34969 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
POLB P06746 1/20 0.42
KDM4E B2RXH2 4/20 0.42
ALDH1A1 P00352 2/20 0.42
ALOX5AP P20292 1/20 0.41
FEN1 P39748 1/20 0.41
ADRB2 P07550 4/20 0.41
SLC6A9 P48067 1/20 0.40
ADRB1 P08588 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29175450 0.92 SLC6A9 (0.44) TP53MAPK1RAB9ALMNAHTT
SCHEMBL577512 0.84 L3MBTL1 (0.39) TP53MAPK1RAB9ALMNAHTT
SCHEMBL8686874 0.83 HPGD (0.42) TP53MAPK1RAB9ALMNASMN1; SMN2
SCHEMBL8681891 0.82 ALDH1A1 (0.41) TP53MAPK1RAB9ALMNAHTT
SCHEMBL576514 0.82 KDM4E (0.39) TP53MAPK1RAB9AHTTSMN1; SMN2
SCHEMBL576756 0.81 ALDH1A1 (0.40) TP53MAPK1RAB9ALMNASMN1; SMN2
SCHEMBL577661 0.81 KDM4E (0.40) TP53MAPK1RAB9ALMNAHTT
SCHEMBL8681741 0.80 PPARG (0.39) TP53MAPK1RAB9AKMT2AKDM4E
SCHEMBL576992 0.79 PPARG (0.40) TP53MAPK1RAB9ALMNASMN1; SMN2
SCHEMBL577696 0.79 SLC6A9 (0.44) PTGDR2ALOX5APFEN1SLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354516-A1 POLYCARBONATE RESIN, METHOD FOR PRODUCING SAME, AND OPTICAL LENS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-11-12 US disclosed
EP-2272889-B1 POLYCARBONATE RESIN HAVING ULTRAVIOLET ABSORBING CAPABILITY, RESIN COMPOSITION AND OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2013-09-04 EP disclosed
US-20120116000-A1 POLYCARBONATE RESIN COMPOSITION, AND PROCESS FOR PRODUCING MOLDED PRODUCTS AND OPTICAL LENS USING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-10 US disclosed
EP-2418253-A1 POLYCARBONATE RESIN COMPOSITION, PROCESS FOR PRODUCING MOLDED ARTICLE THEREFROM, AND OPTICAL LENS Mitsubishi Gas Chemical Company, Inc. (JP) 2012-02-15 EP disclosed
EP-2272889-A1 POLYCARBONATE RESIN HAVING ULTRAVIOLET ABSORBING CAPABILITY, RESIN COMPOSITION AND OPTICAL MATERIAL Mitsubishi Gas Chemical Company, Inc. (JP) 2011-01-12 EP disclosed
US-5780194-A PHOTOSENSITIVE LAYER OF POLYESTER BINDING RESIN, ELECTRIC CHARGE GENERATING MATERIAL, AND HOLE TRANSFERRING MATERIAL MITA INDUSTRIAL CO., LTD. (JP) 1998-07-14 US disclosed