SCHEMBL3367758

SCHEMBL3367758

O=C(O)c1c(Cl)ccc2cc3ccccc3cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
KDM4E B2RXH2 4/20 0.58
HSD17B10 Q99714 4/20 0.58
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
HPGD P15428 2/20 0.58
CYP1A2 P05177 1/20 0.58
GLA P06280 1/20 0.58
CYP2C19 P33261 1/20 0.58
DPP4 P27487 1/20 0.46
GAA P10253 1/20 0.43
ALK Q9UM73 1/20 0.41
SOS1 Q07889 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
HTT P42858 1/20 0.39
CYP2A6 P11509 1/20 0.38
CDC25B P30305 2/20 0.38
PBRM1 Q86U86 1/20 0.38
WDR5 P61964 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30106247 1.00 ALDH1A1 (0.58) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3701843 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3773008 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL27855326 0.87 ALDH1A1 (0.46) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3699078 0.86 MEN1 (0.46) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3706346 0.85 MEN1 (0.44) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3778102 0.85 MEN1 (0.44) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3702460 0.84 ALDH1A1 (0.45) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3146455 0.83 HSD17B10 (0.59) ALDH1A1KDM4EHSD17B10KMT2AMEN1
SCHEMBL3707483 0.83 ALDH1A1 (0.44) ALDH1A1KDM4EHSD17B10KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
US-10188910-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
US-20180126226-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-05-10 US disclosed
US-20180056137-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-03-01 US disclosed
EP-2808063-B1 Golf ball DUNLOP SPORTS CO LTD (JP) 2018-02-21 EP disclosed
US-9873022-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2018-01-23 US disclosed
US-9855467-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2018-01-02 US disclosed
EP-2610291-B1 GOLF BALL DUNLOP SPORTS CO LTD (JP) 2017-12-20 EP disclosed
EP-2460789-B1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-04-19 EP disclosed
CN-104208848-B golf ball 邓禄普体育用品株式会社 2017-04-12 CN disclosed
US-20100035917-A1 PYRROLO[2,3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS 1KK2 INHIBITORS GLAXO GROUP LIMITED (GB) 2010-02-11 US disclosed
EP-1690685-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2009-04-15 EP disclosed
EP-1481973-B1 HETEROCYCLE-BEARING ONIUM SALTS WAKO PURE CHEM IND LTD (JP) 2008-12-31 EP disclosed
EP-1953149-A2 A heterocycle-containing onium salt Wako Pure Chemical Industries, Ltd. (JP) 2008-08-06 EP disclosed
US-20080161520-A1 Heterocycle-bearing onium salts WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-07-03 US disclosed
US-20080146606-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-06-19 US disclosed
US-7318991-B2 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-01-15 US disclosed
EP-1690685-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-08-16 EP disclosed
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2005-10-20 US disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether NOX4, CBR1, CBR3 ALDH1A1 1190/4885KDM4E 2670/4885HSD17B10 1394/4885
US-20100035917-A1 PYRROLO[2,3-B]PYRIDIN-4-YL-BENZENESULFONAMIDE COMPOUNDS AS 1KK2 INHIBITORS PLK2, PDXK, MAP4K2 ALDH1A1 2180/4885KDM4E 594/4885HSD17B10 2320/4885
US-20080146606-A1 NOVEL COMPOUNDS NFKBIA, IKBKG, IKBKE ALDH1A1 4154/4885KDM4E 1848/4885HSD17B10 2210/4885
US-20080161520-A1 Heterocycle-bearing onium salts MCM5, NIT2, PCNA ALDH1A1 2676/4885KDM4E 2415/4885HSD17B10 1400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.