Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 6/20 | 1.00 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363984 | 0.92 | OXTR (0.84) | OXTRAVPR1ASMN1; SMN2POLBHPGD | |
| SCHEMBL5643910 | 0.90 | OXTR (1.00) | OXTRAVPR1ASMN1; SMN2POLBMAPT | |
| SCHEMBL10053396 | 0.80 | SMN1; SMN2 (0.86) | OXTRAVPR1ASMN1; SMN2POLBHPGD | |
| SCHEMBL17340104 | 0.78 | OXTR (0.64) | OXTRAVPR1APOLBHPGDTP53 | |
| SCHEMBL18962718 | 0.78 | OXTR (0.75) | OXTRAVPR1APOLBHPGDMAPT | |
| SCHEMBL10005188 | 0.77 | OXTR (0.77) | OXTRAVPR1ASMN1; SMN2HPGDATM | |
| SCHEMBL744176 | 0.76 | OXTR (1.00) | OXTRAVPR1ASMN1; SMN2POLBMAPT | |
| SCHEMBL798403 | 0.76 | OXTR (0.69) | OXTRAVPR1ASMN1; SMN2HPGDATM | |
| SCHEMBL17340100 | 0.76 | MAPT (0.68) | OXTRAVPR1ASMN1; SMN2MAPTTP53 | |
| SCHEMBL806780 | 0.76 | SMN1; SMN2 (1.00) | OXTRAVPR1ASMN1; SMN2POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |