SCHEMBL3367982

SCHEMBL3367982

CC(=CC(O)CO)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.40
PTGS1 P23219 1/20 0.35
OR51E2 Q9H255 1/20 0.35
TGFBR1 P36897 1/20 0.32
AKR1C3 P42330 1/20 0.31
PTPN11 Q06124 1/20 0.30
APEX1 P27695 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1629103 0.96 AKR1B1 (0.37) AKR1B1PTGS1OR51E2TGFBR1
Ethylene Glycol SCHEMBL1630554 0.96 AKR1B1 (0.37) AKR1B1PTGS1OR51E2TGFBR1
Ethylene Glycol SCHEMBL1630465 0.96 AKR1B1 (0.37) AKR1B1PTGS1OR51E2TGFBR1
SCHEMBL346952 0.82 GABRP (0.32)
SCHEMBL2477920 0.82 GABRP (0.32)
SCHEMBL10537916 0.81 PTPN11 (0.32) PTPN11
SCHEMBL8700596 0.81 AKR1C3 (0.35) PTGS1AKR1C3PTPN11APEX1
SCHEMBL711050 0.81 GAPDH (0.38) PTGS1AKR1C3PTPN11APEX1
SCHEMBL16667 0.81 GAPDH (0.38) PTGS1AKR1C3PTPN11APEX1
Ethylene Glycol SCHEMBL16656014 0.80 PTGS1 (0.33) AKR1B1PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684059-A FLUOROMONOMER, HYDROXYALKYL ACRYLATE OR METHACRYLATE, N-VINYL LACTAM, SULFONIC ACID MONOMER OPTIMERS, INC. 1997-11-04 US claimed
EP-0563047-A4 1994-02-09 EP claimed
EP-0563047-A1 FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS SALAMONE, Joseph C. (US) 1993-10-06 EP claimed
WO-1992011300-A1 FLUORINE CONTAINING SOFT CONTACT LENS HYDROGELS SALAMONE JOSEPH C (US) 1992-07-09 WO claimed
US-4990582-A Wettable, oxygen permeable resistant to protein deposits OPTIMERS, INC. 1991-02-05 US claimed
EP-0253515-A2 Fluorine containing soft contact lens hydrogels OPTIMERS INC. (US) 1988-01-20 EP claimed
WO-2023213700-A1 PREPARATION OF TERMINALLY UNSATURATED (METH)ACRYLATE CROSSLINKERS RÖHM GMBH (DE) 2023-11-09 WO disclosed
CN-102740881-A Methods for orthopoxvirus production and purification TRANSGENE SA 2012-10-17 CN disclosed
EP-1544266-B1 (METH)ACRYLIC COPOLYMER RESIN AND COATING FILM THEREOF MITSUI CHEMICALS INC (JP) 2010-10-13 EP disclosed
CN-101676339-A Microparticles of water-insoluble compound and disperser thereof, their preparation method, and color filter FUJI PHOTO FILM CO LTD 2010-03-24 CN disclosed
US-7186788-B2 (Meth)acrylic copolymer resin and coating film thereof MITSUI CHEMICALS, INC. (JP) 2007-03-06 US disclosed
US-20050222321-A1 Wear/solvent resistance; glass transition temperature; viscoelasticity MITSUI CHEMICAL , INC. 2005-10-06 US disclosed
EP-1544266-A1 (METH)ACRYLIC COPOLYMER RESIN AND COATING FILM THEREOF Mitsui Chemicals, Inc. (JP) 2005-06-22 EP disclosed
CN-1153775-C Organophosphorus compounds for dental polymerizable compositions �����ɷ� 2004-06-16 CN disclosed
US-5300536-A Vinyl compound capable of free radical polymerization TOAGOSEI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-04-05 US disclosed