SCHEMBL8700596

SCHEMBL8700596

CC(=CC(O)CCl)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.35
APEX1 P27695 8/20 0.33
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C9 P11712 1/20 0.32
PTGS1 P23219 1/20 0.31
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL711050 0.81 GAPDH (0.38) AKR1C3APEX1PTGS1PTPN11
SCHEMBL16667 0.81 GAPDH (0.38) AKR1C3APEX1PTGS1PTPN11
SCHEMBL3367982 0.81 AKR1B1 (0.40) AKR1C3APEX1PTGS1PTPN11
SCHEMBL15193351 0.80 ALDH1A1 (0.35) AKR1C3APEX1ALDH1A1TSHR
SCHEMBL15193352 0.80 ALDH1A1 (0.35) AKR1C3APEX1ALDH1A1TSHR
SCHEMBL25273758 0.78 PTGS1 (0.32) AKR1C3APEX1TSHRPTGS1
SCHEMBL1238097 0.77 HDAC1 (0.39) ALDH1A1TSHR
SCHEMBL152165 0.77 HDAC1 (0.39) ALDH1A1TSHR
SCHEMBL20549622 0.77 FFAR1 (0.38)
SCHEMBL2477920 0.77 GABRP (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676420-B1 Aqueous curable resin compositions KANSAI PAINT CO LTD (JP) 1998-09-02 EP disclosed
US-5593731-A STORAGE STABLE POLYMER WITH AMMONIUM, SULFONIUM AND PHOSPHONIUM GROUPS FOR MONOMERS FOR WATERPROOFING KANSAI PAINT COMPANY LIMITED (JP) 1997-01-14 US disclosed
EP-0676420-A2 Aqueous curable resin compositions KANSAI PAINT CO., LTD. (JP) 1995-10-11 EP disclosed