SCHEMBL336806

SCHEMBL336806

O=C(O)CC(CC(=O)O)(OO)C(=O)O.[CaH2]

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
ACLY P53396 3/20 0.34
CPT2 P23786 2/20 0.33
KDM4E B2RXH2 1/20 0.31
FFAR1 O14842 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL27667026 0.97 ALDH1A1 (0.40) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL108616 0.97 ALDH1A1 (0.43) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL28505954 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL988732 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL11021067 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL337214 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2487792 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
Water SCHEMBL2959958 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2966015 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A
SCHEMBL2315211 0.95 ALDH1A1 (0.42) ALDH1A1CYP2D6TSHRCYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118956849-A Preparation method of immobilized lipase and application of immobilized lipase in catalytic synthesis of glyceride 广东药科大学 2024-11-15 CN claimed
CN-116549427-A New use of hydroxycitric acid for treating cholelithiasis and cholecystitis induced by cholelithiasis 时珍本草生物科技(中山)有限公司 2023-08-08 CN claimed
EP-1827139-A2 SUPPLEMENT DIETARY COMPOSITION FOR PROMOTING WEIGHT LOSS Lean Balance Formulations Ltd. (CA) 2007-09-05 EP claimed
US-7214823-B2 Hydroxycitric acid complex metal salts, composition, and methods INDFRAG LIMITED (IN) 2007-05-08 US claimed
US-7208615-B2 Triple mineral salts of (-)-hydroxycitric acid and processes for preparing the same LAILA IMPEX (IN) 2007-04-24 US claimed
US-20070031526-A1 Topical Deodorant Compositions Based on Hydroxycitric Acid BIODERM RESEARCH (US) 2007-02-08 US claimed
WO-2006133543-A1 DIET SUPPLEMENTS FOR WEIGHT LOSS, DAYTIME ENERGY AND NIGHT TIME RELAXATION EVERSLIM FORMULATIONS LTD. (CA) 2006-12-21 WO claimed
US-20060286181-A1 Diet supplements for causing fast weight loss, improving daytime energy, promoting nighttime relaxation and sleep, controlling appetite and/or increasing metabolism 1695047 ONTARIO LTD. (CA) 2006-12-21 US claimed
US-20060240074-A1 Novel triple mineral salts of (-)-hydroxycitric acid and processes for preparing the same LAILA IMPEX (IN) 2006-10-26 US claimed
US-20060210650-A1 Supplemental dietary composition for promoting weight loss HALO FORMULATIONS LTD. (CA) 2006-09-21 US claimed
WO-2005085164-A1 NOVEL TRIPLE MINERAL SALTS OF (-)-HYDROXYCITRIC ACID AND PROCESSES FOR PREPARING THE SAME GOKARAJU GANGA RAJU (IN) 2005-09-15 WO claimed
US-20040259937-A1 Hydroxycitric acid complex metal salts, composition, and methods INDFRAG LIMITED (IN) 2004-12-23 US claimed
US-20040219124-A1 Cosmetic and Pharmaceutical Masks Based on Ion-Pair Delivery System GUPTA SHYAM K (US) 2004-11-04 US claimed
WO-2003092730-A1 HYDROXYCITRIC ACID SALT COMPOSITION AND METHOD OF MAKING UNIBAR CORPORATION (US) 2003-11-13 WO claimed
US-20030207942-A1 Hydroxycitric acid salt composition and method of making UNIBAR CORPORATION (US) 2003-11-06 US claimed
EP-0787489-B1 Composition containing propionyl-L-carnitine and hydroxycitric acid or pantothenic acid SIGMA TAU HEALTHSCIENCE SPA (IT) 2003-07-30 EP claimed
US-20010011081-A1 Pharmaceutical composition comprising L- carnitine or alkanoyl L-carnitine for the prevention and treatment of diseases brought about by lipid metabolism disorders SIGMA-TAU INDUSTRIE PARMACEUTICHE RIUNITE S.P.A. (IT) 2001-08-02 US claimed
US-6217898-B1 ANTICHOLESTEROL AGENTS SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) 2001-04-17 US claimed
WO-2000015051-A1 HYDROXYCITRIC ACID COMPOSITIONS INTERHEALTH NUTRACEUTICALS, INC. (US) 2000-03-23 WO claimed
EP-0787489-A2 Composition containing L-carnitine or alkanoyl-L-carnitine and hydroxycitric acid or pantothenic acid Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1997-08-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060240074-A1 Novel triple mineral salts of (-)-hydroxycitric acid and processes for preparing the same HCAR1, SLC5A6, CA6 ALDH1A1 1206/4885CYP2D6 3023/4885TSHR 3078/4885
US-20030207942-A1 Hydroxycitric acid salt composition and method of making HCAR1, HCAR2, HAAO ALDH1A1 3828/4885CYP2D6 3500/4885TSHR 4034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.