Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14691512 | 0.79 | NFE2L2 (0.37) | NFE2L2CTSSKMOKIF11 | |
| SCHEMBL364870 | 0.78 | P2RX7 (0.36) | P2RX7GRM4KMONOTUMSLC40A1 | |
| SCHEMBL24218360 | 0.76 | NFE2L2 (0.36) | NFE2L2 | |
| SCHEMBL31028560 | 0.76 | MEN1 (0.34) | NFE2L2GRM4KMOKIF11SLC40A1 | |
| SCHEMBL17255057 | 0.76 | MEN1 (0.34) | NFE2L2GRM4KMOKIF11SLC40A1 | |
| SCHEMBL3100708 | 0.75 | NOS3 (0.35) | P2RX7GRM4KMONOTUMSLC40A1 | |
| SCHEMBL5303261 | 0.74 | ALDH1A1 (0.34) | NFE2L2 | |
| SCHEMBL586118 | 0.73 | NFE2L2 (0.48) | NFE2L2SLC40A1 | |
| SCHEMBL6805218 | 0.72 | AAK1 (0.38) | P2RX7KMONOTUM | |
| SCHEMBL31711438 | 0.71 | NFE2L2 (0.35) | NFE2L2KMOKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204642-B1 | FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2010-10-13 | — | — | EP | disclosed |
| US-6939882-B1 | Fungicides | AVENTIS CROPSCIENCES GMBH (DE) | 2005-09-06 | — | — | US | disclosed |
| US-6864265-B2 | Chemokine receptor binding heterocyclic compounds | ANORMED, INC. (CA) | 2005-03-08 | — | — | US | disclosed |
| EP-1204642-A1 | FUNGICIDES | Aventis CropScience GmbH (DE) | 2002-05-15 | — | — | EP | disclosed |
| WO-2001012604-A1 | FUNGICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 2001-02-22 | — | — | WO | disclosed |