SCHEMBL3368840

SCHEMBL3368840

Cc1ccccc1C(=N)N

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.44
F10 P00742 2/20 0.44
F12 P00748 1/20 0.44
F7 P08709 1/20 0.44
F3 P13726 1/20 0.44
PKM P14618 1/20 0.44
TSHR P16473 1/20 0.43
ACHE P22303 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
BLM P54132 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PRSS1 P07477 3/20 0.41
PRSS2 P07478 2/20 0.41
PRSS3 P35030 2/20 0.41
C1S P09871 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11693952 0.98 BLM (0.46) F2F10F12F7F3
Acetic Acid SCHEMBL3155770 0.89 RAB9A (0.47) F2F10NPC1RAB9AKMT2A
SCHEMBL6830746 0.81 TRPA1 (0.44) F2F10F12F7F3
SCHEMBL10495281 0.81 F2 (0.55) F2F10F12F7F3
SCHEMBL28628789 0.81 MYC (0.43) F2F10F12F7F3
SCHEMBL2154043 0.81 MYC (0.61) F2F10F12F7F3
SCHEMBL10824573 0.80 NISCH (0.39) F2F10F7NPC1RAB9A
SCHEMBL1544723 0.79 PLAU (0.55) F2F10F7NPC1RAB9A
SCHEMBL4441911 0.79 CYP3A4 (0.56) TSHRACHEMAOAMAOBALDH1A1
SCHEMBL5900574 0.79 TSHR (0.47) TSHRACHEMAOAMAOBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104177298-B Bis- substitution -4,5- dihydros -1H of 4,4--imidazoles -5- ketone, derivative and its synthetic method 湘潭大学 2018-10-02 CN claimed
CN-104177298-A 4, 4-disubstituted-4, 5-dihydro-1H-imidazole-5-one and derivatives thereof as well as synthesis method thereof UNIV XIANGTAN 2014-12-03 CN claimed
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2026-04-07 US disclosed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
US-20240150506-A1 CURING AGENTS FOR FLUOROELASTOMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
EP-4305096-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS Dupont Specialty Products USA, LLC (US) 2024-01-17 EP disclosed
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
CN-116324539-A Polarizing plate and image display device 住友化学株式会社 2023-06-23 CN disclosed
WO-2022192006-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS DUPONT POLYMERS, INC. (US) 2022-09-15 WO disclosed
WO-2003068757-A1 NOVEL PYRIDIN- AND PYRIMIDIN-DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2003-08-21 WO disclosed
US-4888350-A ANTIFERTILITY AGENTS GRUPPO LEPETIT S.P.A. (IT) 1989-12-19 US disclosed
US-4459302-A CONTRACEPTIVES GRUPPO LEPETIT, S.P.A. (IT) 1984-07-10 US disclosed
EP-0025321-B1 COMPOSITION CONTAINING S-SULFONATED IMMUNOGLOBULIN AND AGGREGATION PREVENTING OR AGGREGATE DISSOCIATING AGENT THEREFOR, AND PROCESSES FOR PREPARING COMPOSITIONS CONTAINING HIGH PROPORTIONS OF MONOMERIC S-SULFONATED IMMUNOGLOBULIN TEIJIN LIMITED (JP) 1984-03-21 EP disclosed
US-4362661-A BASIC AMINO ACID SALT TO PREVENT AGGREGATION TEIJIN LIMITED (JP) 1982-12-07 US disclosed
US-4360457-A AMINO ACID SALT TEIJIN LIMITED (JP) 1982-11-23 US disclosed
US-4303592-A SERINE PROTEASE INHIBITORS CENTER FOR BLOOD RESEARCH, INC. (US) 1981-12-01 US disclosed
EP-0025321-A2 Composition containing S-sulfonated immunoglobulin and aggregation preventing or aggregate dissociating agent therefor, and processes for preparing compositions containing high proportions of monomeric S-sulfonated immunoglobulin TEIJIN LIMITED (JP) 1981-03-18 EP disclosed
EP-0025275-A2 Immunoglobulin-containing composition containing an aggregation preventing or aggregate dissociating agent for the immunoglobulin, and process for preparation thereof TEIJIN LIMITED (JP) 1981-03-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595251-B2 Amidines and amidine analogs for the treatment of bacterial infections and potentiation antibiotics CLIC1, CBR3, CBR1 F2 3549/4885F10 3471/4885F12 3335/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 F2 1117/4885F10 1372/4885F12 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.