SCHEMBL336896

SCHEMBL336896

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2cccc(CCl)c21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 10/20 0.59
MAPT P10636 3/20 0.59
HPGD P15428 2/20 0.59
MEN1 O00255 2/20 0.59
HTT P42858 2/20 0.59
KMT2A Q03164 2/20 0.59
CYP2C19 P33261 1/20 0.59
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
SMAD3 P84022 1/20 0.59
PRMT1 Q99873 1/20 0.59
ACE2 Q9BYF1 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ALDH1A1 P00352 2/20 0.56
ALOX12 P18054 2/20 0.56
CYP2C9 P11712 1/20 0.56
ALOX15 P16050 1/20 0.56
BRCA1 P38398 1/20 0.56
HSD17B10 Q99714 1/20 0.56
GSTP1 P09211 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4743773 0.89 FTO (0.60) FTOMAPTHPGDMEN1HTT
SCHEMBL2314510 0.89 FTO (0.60) FTOMAPTHPGDMEN1HTT
SCHEMBL84112 0.88 FTO (0.59) FTOMAPTHPGDMEN1HTT
SCHEMBL2184643 0.88 FTO (0.59) FTOMAPTHPGDMEN1HTT
Hydrochloric Acid SCHEMBL7640824 0.86 FTO (0.57) FTOMAPTHPGDMEN1HTT
SCHEMBL22110384 0.85 FTO (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL1115891 0.85 HPGD (0.57) FTOMAPTHPGDMEN1HTT
SCHEMBL4825622 0.85 FTO (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL7647553 0.85 FTO (0.56) FTOMAPTHPGDMEN1HTT
SCHEMBL1669688 0.84 HPGD (0.59) FTOMAPTHPGDMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2975406-B1 PROCESSES FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS ENZO LIFE SCIENCES INC (US) 2018-07-18 EP claimed
EP-2975405-B1 PROCESSES FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS ENZO LIFE SCIENCES INC (US) 2018-03-07 EP claimed
EP-2975405-A1 PROCESSES FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS Enzo Life Sciences, Inc. (US) 2016-01-20 EP claimed
EP-2975406-A1 PROCESSES FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS Enzo Life Sciences, Inc. (US) 2016-01-20 EP claimed
EP-2567233-B1 PROCESSES FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS ENZO LIFE SCIENCES INC (US) 2015-11-04 EP claimed
US-9097673-B2 Processes and kits for determining multi-drug resistance of cells ENZO LIFE SCIENCES, INC. (US) 2015-08-04 US claimed
US-20130323773-A1 PROCESSES AND KITS FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS ENZO LIFE SCIENCES, INC. 2013-12-05 US claimed
US-8445271-B2 Processes and kits for determining multi-drug resistance of cells ENZO LIFE SCIENCES, INC. (US) 2013-05-21 US claimed
EP-2567233-A1 PROCESSES AND KITS FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS Enzo Life Sciences, Inc. (US) 2013-03-13 EP claimed
US-8097404-B2 Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORPORATION (US) 2012-01-17 US claimed
WO-2011139634-A1 PROCESSES AND KITS FOR DETERMINING MULTI-DRUG RESISTANCE OF CELLS ENZO LIFE SCIENCES, INC. (US) 2011-11-10 WO claimed
US-20110269168-A1 Processes and kits for determining multi-drug resistance of cells ENZO LIFE SCIENCES, INC. 2011-11-03 US claimed
EP-2107119-B1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane MILLIPORE CORP (US) 2010-05-12 EP claimed
EP-2107119-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane Millipore Corporation (US) 2009-10-07 EP claimed
US-20090246822-A1 Composition for cell permeabilization comprising NOG, HMP, rubidium chloride and/or lithium chloride for detecting living cells on a membrane EMD MILLIPORE CORPORATION 2009-10-01 US claimed
US-20030018457-A1 Biological modeling utilizing image data BIOANALYTICS GROUP, L.L.C., THE 2003-01-23 US claimed
WO-2002099736-A1 BIOLOGICAL MODELING UTILIZING IMAGE DATA PHYSIOME SCIENCES, INC. (US) 2002-12-12 WO claimed
EP-3548006-B1 COMPOSITION FOR USE IN THE TREATMENT OF INTESTINAL ALTERATIONS ALFASIGMA SPA (IT) 2023-11-15 EP disclosed
EP-0603266-A1 USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS MOLECULAR PROBES, INC. (US) 1994-06-29 EP disclosed
WO-1993004192-A1 USE OF HALOALKYL DERIVATIVES OF REPORTER MOLECULES TO ANALYZE METABOLIC ACTIVITY IN CELLS MOLECULAR PROBES, INC. (US) 1993-03-04 WO disclosed