Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84112 | 0.90 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| Hydrochloric Acid SCHEMBL7640824 | 0.89 | FTO (0.57) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL4825622 | 0.88 | FTO (0.56) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL4743773 | 0.86 | FTO (0.60) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL2314510 | 0.86 | FTO (0.60) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL4824384 | 0.86 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL622479 | 0.86 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL16116120 | 0.86 | FTO (0.54) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL2184643 | 0.85 | FTO (0.59) | FTOMAPTHPGDMEN1HTT | |
| SCHEMBL336896 | 0.85 | FTO (0.59) | FTOMAPTHPGDMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472227-B1 | A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | disclosed |
| US-5463027-A | Fluorescence polarazation immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1995-10-31 | — | — | US | disclosed |
| US-5264373-A | Fluorescence polarization immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1993-11-23 | — | — | US | disclosed |
| US-5144030-A | Fluorescene polarization immunoassay for tetrahydrocannabinoids | ABBOTT LABORATORIES (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0457213-A2 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |