SCHEMBL3369451

SCHEMBL3369451

O=C(O)c1c(F)ccc2cc3ccccc3cc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
KDM4E B2RXH2 2/20 0.58
HSD17B10 Q99714 2/20 0.58
CYP1A2 P05177 1/20 0.58
GLA P06280 1/20 0.58
HPGD P15428 1/20 0.58
CYP2C19 P33261 1/20 0.58
GAA P10253 1/20 0.43
HSD17B14 Q9BPX1 1/20 0.42
DHODH Q02127 1/20 0.41
SOS1 Q07889 1/20 0.39
CDC25B P30305 2/20 0.38
ANO1 Q5XXA6 1/20 0.38
WDR5 P61964 1/20 0.38
IDO1 P14902 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
METAP2 P50579 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31429086 1.00 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL3367134 0.83 HSD17B10 (0.59) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL31429106 0.83 HSD17B10 (0.59) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL929603 0.80 ALDH1A1 (0.60) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL43510 0.80 KDM4E (0.60) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL29506855 0.80 KDM4E (0.60) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL4896934 0.79 ALDH1A1 (0.84) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL31125071 0.79 KDM4E (0.69) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL3624397 0.79 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AKDM4EHSD17B10
SCHEMBL3367758 0.79 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230176481-A1 FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2023-06-08 US disclosed
US-10188910-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
US-20180126226-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-05-10 US disclosed
US-20180056137-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2018-03-01 US disclosed
EP-2808063-B1 Golf ball DUNLOP SPORTS CO LTD (JP) 2018-02-21 EP disclosed
US-9873022-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2018-01-23 US disclosed
US-9855467-B2 Golf ball DUNLOP SPORTS CO. LTD. (JP) 2018-01-02 US disclosed
EP-2610291-B1 GOLF BALL DUNLOP SPORTS CO LTD (JP) 2017-12-20 EP disclosed
US-9586094-B2 Golf ball and method for manufacturing the same DUNLOP SPORTS CO. LTD. (JP) 2017-03-07 US disclosed
US-9302158-B2 Golf ball DUNLOP SPORTS CO., LTD. (JP) 2016-04-05 US disclosed
US-7833691-B2 Heterocycle-bearing onium salts WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-11-16 US disclosed
EP-1953149-B1 A heterocycle-containing onium salt WAKO PURE CHEM IND LTD (JP) 2010-10-06 EP disclosed
EP-1690685-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2009-04-15 EP disclosed
EP-1481973-B1 HETEROCYCLE-BEARING ONIUM SALTS WAKO PURE CHEM IND LTD (JP) 2008-12-31 EP disclosed
EP-1953149-A2 A heterocycle-containing onium salt Wako Pure Chemical Industries, Ltd. (JP) 2008-08-06 EP disclosed
US-20080161520-A1 Heterocycle-bearing onium salts WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-07-03 US disclosed
US-7318991-B2 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2008-01-15 US disclosed
EP-1690685-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-08-16 EP disclosed
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2005-10-20 US disclosed
EP-1481973-A1 HETEROCYCLE-BEARING ONIUM SALTS Wako Pure Chemical Industries, Ltd. (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050233253-A1 Diphenylsulfonium compounds in which the S atom is additionally attached to a xanthene-9-onyl-2-yl- or coumarin-7-yl- ring; acid generator for a chemically amplified resist; photopolymerization initiator for polymerizing an epoxide or a vinyl ether NOX4, CBR1, CBR3 ALDH1A1 1190/4885MEN1 1499/4885KMT2A 3769/4885
US-20080161520-A1 Heterocycle-bearing onium salts MCM5, NIT2, PCNA ALDH1A1 2676/4885MEN1 417/4885KMT2A 366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.