SCHEMBL33701

SCHEMBL33701

CC(=O)Nc1ccc(N)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.57
POLB P06746 1/20 0.56
ALDH1A1 P00352 3/20 0.55
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA9 Q16790 2/20 0.53
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.53
KMT2A Q03164 2/20 0.53
BRD4 O60885 1/20 0.53
NR1I2 O75469 1/20 0.53
MB P02144 1/20 0.53
CYP1A1 P04798 1/20 0.53
CA3 P07451 1/20 0.53
CYP3A4 P08684 1/20 0.53
RARG P13631 1/20 0.53
TSHR P16473 1/20 0.53
ALOX5AP P20292 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29415477 1.00 PKM (0.59) PKMSMN1; SMN2POLBALDH1A1CA12
Hydrochloric Acid SCHEMBL7155376 0.98 PKM (0.57) PKMSMN1; SMN2POLBALDH1A1CA12
SCHEMBL6851532 0.85 ALDH1A1 (0.49) PKMSMN1; SMN2POLBALDH1A1MEN1
SCHEMBL4055616 0.85 TDP1 (0.57) PKMSMN1; SMN2POLBALDH1A1CA12
SCHEMBL7509092 0.84 TDP1 (0.60) SMN1; SMN2ALDH1A1CA12CA1CA2
SCHEMBL9009032 0.84 RAB9A (0.54) PKMSMN1; SMN2POLBCA12CA1
SCHEMBL30442658 0.84 TDP1 (0.60) SMN1; SMN2ALDH1A1CA12CA1CA2
Hydrochloric Acid SCHEMBL11740154 0.83 TDP1 (0.55) PKMSMN1; SMN2POLBALDH1A1CA12
Hydrochloric Acid SCHEMBL7516181 0.82 TDP1 (0.58) SMN1; SMN2ALDH1A1CA12CA1CA2
SCHEMBL16817764 0.82 ALOX15 (0.45) PKMSMN1; SMN2POLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4585 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP claimed
EP-3464247-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'Oréal (FR) 2019-04-10 EP claimed
WO-2017202884-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2017-11-30 WO claimed
EP-3096735-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME Combe International Ltd. (US) 2016-11-30 EP claimed
CN-105916482-A Gradual hair color compositions and methods of use thereof 酷姆国际公司 2016-08-31 CN claimed
WO-2015112789-A1 GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME COMBE INTERNATIONAL LTD. (US) 2015-07-30 WO claimed
EP-0850636-B2 Composition for the oxidative dyeing of keratinic fibres and dyeing process using this composition OREAL (FR) 2013-11-20 EP claimed
CN-101444460-B Oxidation dye composition, oxidation dyeing process and use OU LAIYA 2013-08-14 CN claimed
EP-0728466-A1 Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process L'OREAL (FR) 1996-08-28 EP claimed
US-5478359-A Applying a hair dyes L'OREAL (FR) 1995-12-26 US claimed
EP-0658094-A1 OXIDATIVE KERATIN FIBRE DYEING COMPOSITION CONTAINING A PARA-AMINOPHENOL, A META-AMINOPHENOL AND AN ORTHO-AMINOPHENOL, AND DYEING METHOD USING SAID COMPOSITION L'OREAL (FR) 1995-06-21 EP claimed
CN-1096797-A They carry out painted method dyeing composition for keratinous fibres and application OREAL (FR) 1994-12-28 CN claimed
WO-1994028864-A1 OXIDATIVE KERATIN FIBRE DYEING COMPOSITION CONTAINING A PARA-AMINOPHENOL, A META-AMINOPHENOL AND AN ORTHO-AMINOPHENOL, AND DYEING METHOD USING SAID COMPOSITION L'OREAL (FR) 1994-12-22 WO claimed
EP-0605320-A1 Dye composition for keratinic fibres based on paraphenylenediamine, metaphenylenediamines and benzimidazol derivates, and the dyeing process using same L'OREAL (FR) 1994-07-06 EP claimed
EP-0589952-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS. OREAL (FR) 1994-04-06 EP claimed
EP-0366542-B1 5-SUBSTITUTED ORTHO-AMINOPHENOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE OXIDATION DYEING OF KERATINIC FIBRES L'OREAL (FR) 1993-07-14 EP claimed
WO-1992022525-A1 USE OF SUPLHUROUS METAAMINOPHENOLS FOR DYING KERATINIC FIBRES, TINCTORIAL COMPOSITIONS AND NOVEL COMPOUNDS L'OREAL (FR) 1992-12-23 WO claimed
EP-0366542-A1 5-Substituted ortho-aminophenols, process for their preparation and their use in the oxidation dyeing of keratinic fibres L'OREAL (FR) 1990-05-02 EP claimed