SCHEMBL3370101

SCHEMBL3370101

O=C(O)c1ccc2ccccc2c1[Cu]

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WDR5 P61964 1/20 0.66
LDHA P00338 1/20 0.63
NR4A1 P22736 1/20 0.59
NR4A2 P43354 1/20 0.59
NR4A3 Q92570 1/20 0.59
CDC25B P30305 1/20 0.52
ALDH1A1 P00352 6/20 0.47
HPGD P15428 5/20 0.47
LMNA P02545 1/20 0.47
CSNK2A2 P19784 1/20 0.47
CSNK2B P67870 1/20 0.47
CSNK2A1 P68400 1/20 0.47
KDM4E B2RXH2 3/20 0.46
CYP1B1 Q16678 2/20 0.46
GLA P06280 2/20 0.46
ABCG2 Q9UNQ0 1/20 0.46
GAA P10253 1/20 0.46
CYP1A1 P04798 1/20 0.45
SOS1 Q07889 1/20 0.45
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3372115 0.80 WDR5 (0.66) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL895573 0.79 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL29721418 0.79 WDR5 (1.00) WDR5LDHANR4A1NR4A2NR4A3
Phenanthrene SCHEMBL31651179 0.79 NR4A1 (0.75) WDR5LDHANR4A1NR4A2NR4A3
Phenanthrene SCHEMBL29265471 0.79 NR4A1 (0.75) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL485599 0.78 WDR5 (0.68) WDR5LDHANR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL2099330 0.78 LDHA (1.00) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL33850 0.78 WDR5 (0.68) WDR5LDHANR4A1NR4A2NR4A3
SCHEMBL164035 0.78 WDR5 (0.68) WDR5LDHANR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL3770341 0.78 LDHA (1.00) WDR5LDHANR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741983-B2 Antifouling coating composition including a metal-containing copolymer, 4,5-dichloro-2-N-octyl-4-isothiazolin-3-one, and metal-pyrithione compound and using thereof CHUGOKU MARINE PAINTS, LTD. (JP) 2014-06-03 US disclosed
EP-1457531-B1 ANTIFOULING PAINT COMPOSITION, ANTIFOULING PAINT FILMS, AND SHIPS, UNDERWATER STRUCTURES, FISHING GEAR AND FISHING NETS COVERED WITH THE FILMS CHUGOKU MARINE PAINTS (JP) 2010-10-13 EP disclosed
EP-1457531-A1 ANTIFOULING PAINT COMPOSITION, ANTIFOULING PAINT FILMS, AND SHIPS, UNDERWATER STRUCTURES, FISHING GEAR AND FISHING NETS COVERED WITH THE FILMS CHUGOKU MARINE PAINTS, LTD. (JP) 2004-09-15 EP disclosed