SCHEMBL3370869

SCHEMBL3370869

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nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.60
LMNA P02545 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
PDE4A P27815 1/20 0.38
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
TP53 P04637 1/20 0.32
TOP1 P11387 1/20 0.32
HIF1A Q16665 1/20 0.32
GALR3 O60755 1/20 0.32
PNP P00491 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29752538 1.00 KDM4E (0.60) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL123685 1.00 KDM4E (0.60) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL3685090 1.00 KDM4E (0.60) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL26661419 1.00 KDM4E (0.60) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL6330240 0.95 KDM4E (0.54) KDM4ELMNAL3MBTL1TDP1PDE4A
Formaldehyde SCHEMBL21638814 0.94 KDM4E (0.54) KDM4ELMNAL3MBTL1TDP1PDE4A
Meglumine SCHEMBL29757165 0.92 KDM4E (0.76) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL9444652 0.85 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL29344590 0.85 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A
SCHEMBL5551085 0.85 LMNA (0.65) KDM4ELMNAL3MBTL1TDP1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7846939-B2 Salts and mixture of 9-oxoacridine-10-acetic acid with 1-alkylamino-1-desoxy-polyols, pharmaceutical compositions containing said agents and treatment methods EPHAG AS (EE) 2010-12-07 US disclosed
EP-1970372-B1 SALTS OF 9-OXOACRIDINE-10-ACETIC ACID WITH 1-ALKYLAMNO-1-DESOXY-POLYOLS EPHAG AS (EE) 2010-11-03 EP disclosed
US-20100144780-A1 Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods PJSC PHARMSYNTHEZ (RU) 2010-06-10 US disclosed
EP-1970372-A2 SALTS OF 9-OXOACRIDINE-10-ACETIC ACID WITH 1-ALKYLAMNO-1-DESOXY-POLYOLS EPhaG AS (EE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144780-A1 Salts and Mixture of 9-Oxoacridine-10-Acetic Acid with 1-Alkylamino-1-Desoxy-Polyols, Pharmaceutical Compositions Containing Said Agents and Treatment Methods ADSL, ACMSD, ASS1 KDM4E 3727/4885LMNA 621/4885L3MBTL1 4248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.