Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10391939 | 0.79 | KEAP1 (0.61) | TSHRALDH1A1KMT2ASMN1; SMN2FFAR4 | |
| SCHEMBL10309404 | 0.77 | FFAR4 (0.57) | ALDH1A1KMT2AFFAR4CYTH2 | |
| SCHEMBL11672581 | 0.77 | KEAP1 (0.69) | TSHRALDH1A1KMT2AKEAP1NFE2L2 | |
| SCHEMBL29812756 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1KEAP1NFE2L2POLB | |
| SCHEMBL11229321 | 0.76 | TSHR (0.52) | TSHRALDH1A1KMT2ASMN1; SMN2FFAR4 | |
| SCHEMBL2004599 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1KEAP1NFE2L2POLB | |
| SCHEMBL27182731 | 0.76 | TSHR (0.56) | TSHRALDH1A1KMT2ASMN1; SMN2FFAR4 | |
| SCHEMBL28246241 | 0.75 | KEAP1 (0.61) | TSHRALDH1A1KMT2ASMN1; SMN2KEAP1 | |
| SCHEMBL9246855 | 0.74 | KEAP1 (0.39) | TSHRALDH1A1KMT2ASMN1; SMN2FFAR4 | |
| SCHEMBL3823304 | 0.74 | FFAR4 (0.56) | TSHRALDH1A1KMT2ASMN1; SMN2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114163400-B | Cyclohexanedione-benzothiadiazine compound and application thereof | 东莞市东阳光农药研发有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-114163400-A | Cyclohexanedione-benzothiadiazine compound and application thereof | 东莞市东阳光农药研发有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-114163430-A | Benzothiadiazine derivative and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-8809267-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20140051626-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-02-20 | — | — | US | disclosed |
| US-8513186-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| EP-2162432-A2 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2010-03-17 | — | — | EP | disclosed |
| US-20090186869-A1 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186869-A1 | Antiviral compounds | MAVS, EIF2AK2, ZC3HAV1 | TSHR 4853/4885ALDH1A1 3957/4885KMT2A 3803/4885 |
| US-20140051626-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | TSHR 4853/4885ALDH1A1 3957/4885KMT2A 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.