Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 14/20 | 0.79 |
| ▸ | HTT | P42858 | 2/20 | 0.79 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.71 |
| ▸ | RAD52 | P43351 | 2/20 | 0.71 |
| ▸ | APAF1 | O14727 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065524 | 1.00 | DNM1 (0.79) | DNM1HTTHSP90AA1RAD52APAF1 | |
| SCHEMBL13923673 | 1.00 | DNM1 (0.79) | DNM1HTTHSP90AA1RAD52APAF1 | |
| SCHEMBL16076283 | 0.97 | DNM1 (0.83) | DNM1HTTHSP90AA1RAD52APAF1 | |
| SCHEMBL22782138 | 0.97 | DNM1 (0.83) | DNM1HTTHSP90AA1RAD52APAF1 | |
| SCHEMBL22782137 | 0.97 | DNM1 (0.83) | DNM1HTTHSP90AA1RAD52APAF1 | |
| SCHEMBL16171664 | 0.97 | DNM1 (0.83) | DNM1HTTHSP90AA1RAD52APAF1 | |
| SCHEMBL17702586 | 0.97 | DNM1 (0.83) | DNM1HTTHSP90AA1RAD52APAF1 | |
| Didecyldimethylammonium SCHEMBL8578983 | 0.95 | DNM1 (0.79) | DNM1HTTHSP90AA1RAD52APAF1 | |
| Hydrochloric Acid SCHEMBL5444661 | 0.95 | DNM1 (0.84) | DNM1HTTHSP90AA1RAD52APAF1 | |
| Didecyldimethylammonium SCHEMBL22721358 | 0.95 | DNM1 (0.84) | DNM1HTTHSP90AA1RAD52APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230248805-A1 | INHIBITION OF ENDOSOMAL TOLL-LIKE RECEPTOR ACTIVATION | DUKE UNIVERSITY | 2023-08-10 | — | — | US | disclosed |
| US-20180177690-A1 | COMPOSITION FOR LIFTING COLOR AND/OR ALTERING THE COLOR OF KERATINOUS SUBSTRATES | L'OREAL (FR) | 2018-06-28 | — | — | US | disclosed |
| US-9901553-B2 | Method of modulating the activity of a nucleic acid molecule | DUKE UNIVERSITY (US) | 2018-02-27 | — | — | US | disclosed |
| US-9827185-B2 | Dyeing composition comprising at least one fatty substance, at least one oxidizing agent and at least one non-ionic, anionic and amphoteric surfactant | L'OREAL (FR) | 2017-11-28 | — | — | US | disclosed |
| US-20170095503-A1 | INHIBITION OF ENDOSOMAL TOLL-LIKE RECEPTOR ACTIVATION | DUKE UNIVERSITY (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170022313-A1 | LACTAMIC POLYMER CONTAINING AN ACETOACETATE MOIETY | ISP INVESTMENTS LLC (US) | 2017-01-26 | — | — | US | disclosed |
| US-9505862-B2 | Polymers containing an acetoacetate moiety | ISP INVESTMENTS LLC (US) | 2016-11-29 | — | — | US | disclosed |
| US-9468650-B2 | Inhibition of endosomal toll-like receptor activation | DUKE UNIVERSITY (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160250165-A1 | Method of Modulating the Activity of a Nucleic Acid Molecule | DUKE UNIVERSITY (US) | 2016-09-01 | — | — | US | disclosed |
| US-9340591-B2 | Method of modulating the activity of a nucleic acid molecule | DUKE UNIVERSITY (US) | 2016-05-17 | — | — | US | disclosed |
| US-7326256-B2 | Composition for the oxidation dyeing of keratin fibers, comprising at least one non-oxyalkenylated fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one amide of an alkanolamine and a C14-C30 fatty acid | L'ORéAL S.A. (FR) | 2008-02-05 | — | — | US | disclosed |
| US-7323015-B2 | Oxidation dyeing composition for keratin fibers comprising a cationic poly(vinyllactam) and at least One C10-C14 fatty alcohol, methods and devices for oxidation dyeing | L'OREAL S.A. (FR) | 2008-01-29 | — | — | US | disclosed |
| US-7261743-B2 | Dicationic compounds for dyeing human keratin fibers, and compositions comprising them | L'OREAL (FR) | 2007-08-28 | — | — | US | disclosed |
| US-7223294-B2 | Composition for the oxidation dyeing of keratin fibres, comprising a polyoxyalkylenated carboxylic acid ether, an associative polymer and an unsaturated fatty alcohol | L'OREAL (FR) | 2007-05-29 | — | — | US | disclosed |
| US-7217298-B2 | Ready-to-use bleaching compositions, preparation process and bleaching process | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| US-7204859-B2 | Composition for the oxidation dyeing of keratin fibers, comprising at least one fatty alcohol, at least one oxidation dye, at least one associative polymer, and at least one compound chosen from fatty acid esters and metal oxides | L'OREAL S.A. (FR) | 2007-04-17 | — | — | US | disclosed |
| US-7204858-B2 | Composition for the oxidation dyeing of keratin fibres, comprising an oxyalkylenated carboxylic acid ether and a fatty-chain quaternized cellulose | L'OREAL (FR) | 2007-04-17 | — | — | US | disclosed |
| US-7198649-B2 | Oxidation dyeing composition for keratinous fibers comprising glycerine and a polyol other than glycerine in a specific ratio | L'OREAL (FR) | 2007-04-03 | — | — | US | disclosed |
| US-7175674-B2 | Oxidation dye composition for keratin fibres comprising a nonionic amphiphilic polymer | L'OREAL S.A. (FR) | 2007-02-13 | — | — | US | disclosed |
| US-7172631-B2 | Dyeing composition for human keratinous fibers with oxidation dyes and dicationic compounds | L'OREAL S.A. (FR) | 2007-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180177690-A1 | COMPOSITION FOR LIFTING COLOR AND/OR ALTERING THE COLOR OF KERATINOUS SUBSTRATES | KRT18, DSG1, VCL | DNM1 2532/4885HTT 3690/4885HSP90AA1 4387/4885 |
| US-20170095503-A1 | INHIBITION OF ENDOSOMAL TOLL-LIKE RECEPTOR ACTIVATION | TLR3, TLR9, TLR1 | DNM1 873/4885HTT 3541/4885HSP90AA1 1598/4885 |
| US-20230248805-A1 | INHIBITION OF ENDOSOMAL TOLL-LIKE RECEPTOR ACTIVATION | TLR3, TLR9, TLR1 | DNM1 873/4885HTT 3541/4885HSP90AA1 1598/4885 |
| US-20160250165-A1 | Method of Modulating the Activity of a Nucleic Acid Molecule | NSUN2, POLRMT, POLM | DNM1 575/4885HTT 433/4885HSP90AA1 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.