Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 18/20 | 0.45 |
| ▸ | MAOB | P27338 | 18/20 | 0.45 |
| ▸ | KDM1A | O60341 | 17/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14042739 | 1.00 | MAOA (0.45) | MAOAMAOBKDM1A | |
| SCHEMBL11345821 | 0.81 | MAOA (0.45) | MAOAMAOBKDM1A | |
| SCHEMBL10676812 | 0.72 | GAA (0.42) | — | |
| SCHEMBL2481698 | 0.72 | KDM1A (0.59) | MAOAMAOBKDM1A | |
| SCHEMBL10813259 | 0.72 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL14652769 | 0.70 | KDM1A (0.60) | MAOAMAOBKDM1A | |
| SCHEMBL3372805 | 0.70 | NOS3 (0.30) | — | |
| SCHEMBL8720460 | 0.69 | KDM1A (0.42) | MAOAMAOBKDM1A | |
| SCHEMBL11499118 | 0.68 | KDM1A (0.43) | MAOAMAOBKDM1A | |
| SCHEMBL10407205 | 0.68 | KDM1A (0.36) | MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383859-B2 | Methods of preparing primary, secondary and tertiary carbinamine compounds in the presence of ammonia | THADANI AVINASH N (CA) | 2013-02-26 | — | — | US | disclosed |
| US-20100174090-A1 | METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA | THADANI AVINASH N | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174090-A1 | METHODS OF PREPARING PRIMARY, SECONDARY AND TERTIARY CARBINAMINE COMPOUNDS IN THE PRESENCE OF AMMONIA | HNMT, AADAT, DAO | MAOA 45/4885MAOB 69/4885KDM1A 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.