SCHEMBL3372867

SCHEMBL3372867

c1ccc(CSc2cccc(N(c3ccccc3)c3ccccc3)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.47
MAOB P27338 3/20 0.47
SLC6A4 P31645 1/20 0.42
CYP3A4 P08684 1/20 0.40
DAO P14920 1/20 0.40
DHFR P00374 1/20 0.39
SCN9A Q15858 1/20 0.39
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ELANE P08246 1/20 0.37
METAP2 P50579 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375843 0.86 BCHE (0.40) MAOAMAOBSLC6A4
SCHEMBL3408112 0.80 INSR (0.37) MAOAMAOBSLC6A4
SCHEMBL4864686 0.80 INSR (0.37) MAOAMAOBSLC6A4
SCHEMBL30990576 0.78 TP53 (0.54) MAOAMAOBSLC6A4CYP3A4DAO
SCHEMBL22492228 0.78 CRHBP (0.44) MAOAMAOBSLC6A4DAOPOLB
SCHEMBL1322419 0.78 MAOB (0.51) MAOAMAOBSLC6A4CYP3A4DHFR
SCHEMBL332623 0.76 MAOA (0.63) MAOAMAOBSLC6A4CYP3A4DAO
SCHEMBL19973146 0.76 MAOA (0.51) MAOAMAOBSLC6A4CYP3A4DAO
SCHEMBL3373930 0.75 HTR2C (0.44) MAOAMAOBSLC6A4CYP3A4POLB
SCHEMBL1323306 0.74 MAOB (0.52) MAOAMAOBSLC6A4CYP3A4DAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236488-A1 Materials, methods and uses for photochemical generation of acids and/or radical species The Arizona Board of Regents on behalf of the University of Arizona (US) 2010-10-06 EP disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
EP-1390664-A4 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES UNIV ARIZONA (US) 2008-01-02 EP disclosed
US-20070020479-A1 Luminescent-polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-01-25 US disclosed
US-20050173683-A1 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZ BD OF REGENTS ON BEHALF OF THE UNIV OF AZ (US) 2005-08-11 US disclosed
EP-1390664-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES The Arizona Board of Regents (US) 2004-02-25 EP disclosed
WO-2002079691-A1 MATERIALS, METHODS, AND USES FOR PHOTOCHEMICAL GENERATION OF ACIDS AND/OR RADICAL SPECIES THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2002-10-10 WO disclosed